Objective: to observe the liver resolve depression the treatment of coronary heart disease angina pectoris clinical efficacy and safety with anxiety disorders.Methods: refer to the ancient medical literature "obstruction of pain" and "Depression syndrome" part, discuss the disease origin, etiology and pathogenesis of bluff and treatment;Based on the principle of randomized, controlled clinical trial, 100 patients with standard were randomly divided into experimental group and the control group.On the basis of conventional western medicine treatment, patients with liver resolve depression, the control group and the heart can decide xinkeshu, jialeding. Observing two groups of patients with chest pain symptoms integral change, significant efficiency and total effective rate, HAMA anxiety self-assessment rating scale change and reduction rate, change of TCM syndrome integral, significant efficiency and total effective rate index, compare the curative effect of two groups.Results: Theoretical research results confirmed that the pathogenesis of coronary heart disease angina pectoris with anxiety disorders for "liver disorders, liver fire, fire, the one mind", its treatment for the liver resolve depression, purging fire, nerves, heart stagnation ". Screening of drugs: radix bupleuri, gardenia, radix paeoniae alba, bitter orange, rhizoma ligustici wallichii, perfume, rhizoma corydalis, radix curcumae. Clinical trial results: experimental group of chest pain points lower than the control group(P < 0.05), chest pain in trial group(44.00%), the total effective rate(88.00%) and control group of chest pain show efficiency(36.00%), the total effective rate(70.00%) compared with significant difference(P < 0.05).Experimental group HAMA anxiety self-assessment scale reduction is better than that of control group(P < 0.05);Test anxiety disorders curative effect is significant efficiency(38.00%), the total effective rate(86.00%) and control group efficiency(16.00%), total effective rate(40.00%) compared with difference was statistically significant(P < 0.05).Group of TCM syndrome score lower than the control group(P < 0.05) : experimental group show the efficiency of syndromes(48.00%), the total effective rate(90.00%) and control group efficiency(10.00%), total effective rate(34.00%) compared with difference was statistically significant(P < 0.05).And the two groups before and after treatment the blood routine, liver and kidney functions are no exception.Conclusion: this study confirmed that the liver resolve depression party on the curative effect of coronary heart disease angina pectoris patients with anxiety disorder with no adverse reaction, which provide the basis for its clinical application. |