| Objective To observe the efficacy of Flupentixol and Melitracen in combination treatment of chronic gastritis accompanied with somatization. Methods In this research, we conduct field survey to collect directly the patient information of chronic gastritis in digestive clinics. And through a signed informed consent, the participants are grouped into the control group with the treatment of the psychological counseling and digestive drugs and intervention group with in combination treatment of flupentixol and melitracen in the base of control group treatment. Repeated measures analysis of variance method is analyzed the differences of inside and outside groups with multiplicate somatization scores.somatization total scores and curative effect self-evaluation score by Symptom Check List 90 and curative effect of feedback questionnaire before and after 4 weeks treatment. Finally, we discuss and analyze the optimal effectiveness between two different treatments. Results (1) Chronic gastritis patients have a various of concomitant somatization symptoms in digestive clinics by field survey. (2) Elderly, women, retirement and low education degree, these four social demographic characteristics are associated with the onset of chronic gastritis accompanied with somatization symptoms. (3)Method in the intervention group and the control group have a certain curative effect before and after 4 weeks treatment, include hands and feet heaviness (F=6.601, P<0.05).body feebleness (F=12.555, P<0.05),throat infarction sense (F=4.958,P<0.05),body tingling (F=10.962, P<0.05),muscle ache (F=15.463, P<0.05), Nausea and discomfort (F=59.503, P<0.05),waist pain (F=59.503,P<0.05),chest pain (F=7.083, P<0.05). Moreover. Method for improvement of somatization symptoms in treatment group compared with the control methods have good curative effect, include Paroxysmal cold and hot feeling (F=4.552, P<0.05),dizzy feeling(F=16.208, P<0.05),headache feeling(F=4.187, P<0.05).(4)There is statistically significant difference in curative effect self-feeling scores (F=17.386, P<0.05) and somatization total scores (F=46.390, P<0.05) before and after 4 weeks treatment of two groups. Moreover, the difference is statistically significant with curative effect self-feeling scores (F=19.168, P<0.05)and somatization total scores (F=4.528, P<0.05) between two groups,that is to say,the patients thought that the intervention group curative effect is superior to control group. Conclusion (1) Digest clinic physician needs to focus on patients with chronic gastritis which has in combination with a variety of somatization symptoms, and needs to make patient’s comprehensive treatment strategy according to their social demographic characteristics such as gender, age, education level and occupation. (2) The treatment effect of psychological counseling and digestive medicine is better than traditional medicinal treatment to not only digestive symptoms but also somatization symptoms of chronic gastritis patient. (3) The treatment in combination with new type of antidepressant may be better than not have combined with it to improve somatization symptoms and their self-feeling scores. |
