To Observe The Clinical Curative Effect Of Chronic Urticaria Jiawei Huangqi Guizhi Five Soup Combined With Mizolastine In The Treatment Of

Objective:To observe the clinical curative effect of Jiawei Huangqi Guizhi five soupcombined with mizolastine in the treatment of chronic urticaria.Methods:a non randomized controlled trial methods of open, in the outpatient department of dermatology patients article five hospitals in Changshou City during 2013 January to 2014 June 74 patients with chronic urticaria is selected to meet the inclusion criteria were divided into treatment group (Jiawei Huangqi Guizhi five Soup+mizolastine) in 40 cases, the control group (34 cases, mizolastine) for 12 weeks, in the end of the treatment period the short-term curative effect observation. Recent curative effect of reference in Europe in the 1995 MTLOR standard (i.e. the symptoms of chronicurticaria score) skin disease quality of life index and the improved version of the Cardiff University in the United Kingdom (DLQI), after the end of treatment to cure the patientsat 1,3,6 months in 3 point were followed up observation of long term efficacy of the two groups.Results:Treatment group, the recent clinical symptom improvement rate was 82.5%, control group was 52.94%, two groups compared with significant difference (P< 0.05), and the treatment group in improving the wheal diameter, number of wheal, degree of itching, lasting time was significantly better than the control group (P< 0.01). Treatment group, the quality of life index improvement rate was 62.5%, is 32.25% in the control group, two groups compared with significant difference (P< 0.05) and improve the feel, daily life, leisure and entertainment, study and work, interpersonal relationships, etc. in the quality of life of individual, the treatment group was better than the control group (P< 0.01), but two groups of patients in terms of treatment costs energy no significant difference (P> 0.05), the treatment group in improving clinical symptom score, quality of life scores and TCM symptoms score were significantly better than the control group (P< 0.01). Long-term efficacy compared treatment group the recurrence rate of 10.53%, control group, the recurrence rate was 37.50%, treatment group the long-term curative effect is better than that of the control group (P<0.05). Two groups of patients during treatment and there were no serious adverse reactions.Conclusion:Astragalus cassia twigs Five Decoction Combined with mizolastine in the treatment of chronic urticaria is clear, high safety, and has better clinical application value, the research to explore the therapeutic method of chronic urticaria is moreeffective, and provides a new idea for clinical rich theory of motherland medicine to treat this disease.