Case Analysis And Clinical Study Of 30 Cases Of Hyperlipidemia Acute Pancreatitis

Objective:Comparisons are made between hyperlipidemia and acute biliary pancreatitis by analyzing their clinical features and treatments. Thus, awareness of acute hyperlipidemic pancreatitis can be raised so as to improve the clinical treatment.Method:Retrospective studies were given to the clinical information of 30 complete cases of HLAP patients who had been hospitalized by Ji Lin Hospital Attached to Ji Lin University from Jan.,2012 to Mar.,2015.33 cases of diagnosed ABP patients with complete clinical materials were chosen at random as the control group. Ranson Scores, CTSI, concomitant diseases, complications, treatments, prognosis and so on were collected from these two groups. And then the results were statistically analyzed.Result:(1)The average age of onset of HLAP was obviously lower than ABP group (P<0.01). The ratio and weight index of male sufferers from HLAP group was significantly higher than ABP group (P<0.05).(2)TG, TC and Apo-B of HLAP group were much higher, while low density lipoprotein cholesterol was much lower than ABP group. And the comparisons were of great statistical meaning (P<0.01, P <0.05).While the differences of Apo-A and High density lipoprotein cholesterol of these two groups had no statistical meaning (P>0.05).(3)HLAP patients had lower levels of AMY, UAMY and LDH than ABP group (P<0.01, P<0.05); while their blood glucose, CRP levels were higher than ABP group (P<0.01). While the differences of HCT of these two groups had no statistical meaning (P>0.05) (4)CTSI had no great difference in these 2 groups(P>0.05).(5)Differences in renal inadequacy and multiple organ failure were statistically significant (P<0.05). There were no obvious differences in the occurrence of ARDS, pancreatic pseudocyst, hepatic dysfunction, pancreatic encephalopathy, cardiac insufficiency, gastrointestinal bleeding, seroperitoneum, pancreatic necrosis and pancreatic abscess in these 2 groups (P>0.05). (6).The rate of local complications had no statistical meaning in the comparison, the patients from HLAP group had a significant complication increase in the overall body (P>0.05).(7) There were no statistical meaning in the number of operations and death rate and the recurrence rate (P>0.05) of the patients underwent.Conclusion:(1)HLAP happens more frequently in adolescent males.(2)HLAP patients usually suffer serious lipid metabolism disorder, with significant increase in TG.(3)HLAP patients have a moderate increase in AMY and UAMY.(4)HLAP patients are often accompanied by fatty liver and diabetes.(5) Besides AP routine treatment, lipid-lowering and blood glucose control should also be conducted.