| Objective: This paper discusses the clinical curative effect of Qi-Zhu-Jian-Pi-Tiao-Chang-Yin, based on the method of invigorating spleen and supplementingqi,removing heat-phlegm,promoting flow of qi and blood circulation and dredging,in treating diabetic constipation, and to explore the mechanism of its, provide new and more effective reference for the clinical treatment of diabetic constipation.Methods: By collecting the cases,70 cases in total, of patients,who met the inclusion criteria of diabetic constipation in Endocrine Outpatient and ward of the Affiliated Hospital of Shandong University of TCM during May.2013 to Nov.2014.All patients were randomly divided into two groups, the treatment group 35 cases, control group 35 cases, of which 64 patients completed the trial, 2 cases of falling off, 1 cases removed, 3 cases of suspension, the last observation of treatment group 32 cases, control group 32 cases.The treatment group was given oral Qi-Zhu-Jian-Pi-Tiao-Chang-Yin,the control group was given citrate mosapride.Treatment course of both group was 3 weeks.Glycated albumin, Bristol score, Cleveland score of fecal constipation(CCS), TCM symptom score were recorded and analyzed.Results: After the treatment,all the symptoms were improved significantly in both groups,compared with the scores before treatment(P<0.05).The result of the treatment group’s clinical total effective rate of the treatment group, glycated albumin, Bristol score, CCS score, each stool defecation time, TCM symptom scores is significantly better than that of the control group’s(P < 0.05).The treatment group’s improvement of every single symptom is significantly better than that of the control group’s.Conclusion: Qi-Zhu-Jian-Pi-Tiao-Chang-Yin,based on the method of invigorating spleen and supplementing qi,removing heat-phlegm,promoting flow of qi and blood circulation and dredging, has significant therapeutic effect for diabetic constipation, stool type and obviously improves constipation symptoms, shortens defecation’s time, at the same time can reduce the blood sugar.So it can treate both symptoms and root causes,and also is one of effective method in the clinical treatment of diabetic constipation. |
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