The Clinical Study Of Risk Factors Affecting The Occurrence Of Early Complication In Acute Spinal Cord Injury

Objective: Acute Spine Cord Injury(ASCI) is a severe injury,ASCI may cause long-lasting dysfunction in many organ systems such as respiratoy system,urinary system,cardiovascular system,alimetary system,deep venous trombosis in early phase of injury, and together with permanent change of function, lead to a higher morbidity together with a lower quality of life.Use matched retrospective study method and Logistic regression analysis method to research possible risk factors of early complication in Acute Spinal Cord Injury.Methods:Clinical information of 416 patients hopitalized in the First affiliated hosiptal of Dalian Medical Universit from January 1 2004 to September 30 2014 with ASCI was analyzed retrospectively. Collected gender, age, type and level of injury, surgery,glucocorticoid used and early complications of SCI patients. Use chi-square test to single factor analysis, all statistical significant factors(p<0.05) into unconditionaled logistic regression model, use backward conditional method. There was a statistical significance, when P< 0.05 occurred with two-sided test,all analysis were performed by spss 17.0.Results: 335 males and 81 females in 416 patients,206 in cevical injuries,145 in thracic injuries,65 in lumbar injuries.Incidence of early complications is 19.95%,28.6% in pulmonary infection(n=39),22.3% in hyponatremia(n=31),20.86% in urinary tract infection(n=29),12.23% in cardiovascular disease(n=17),8.63% in alimetary system(n=12),6.48% in deep venous thrombosis(n=9),1.44% in pulmonary embolism(n=2).36 patients are developed with 2 complications,and patients with three or more complications are 9.Age ≥60(OR=2.084, P=0.017), complete spinal cord injury(OR=4.388, P=0.000), injury level was cervical(OR=2.793, P=0.034) and thoracic vertebra(OR=2.582, P=0.040)and glucocorticoid used(OR=2.080, P=0.006)were risk factors affecting the occurrence of early complication in acute spinal cord injury.Conclusion: Early complication of acute spinal cord injury is affected by age, type and level of injury and glucocorticoid used.