Relationship Of Superficial Bladder Cancer Recurrence And Nonspecific Cystitis

ObjectiveA retrospective study of ways to analyze the bladder superficial bladder cancer after infusion duration and recurrence of complications of chemotherapy patient relationship. Further exploration of the complex impact of non-specific inflammation of the bladder cancer bladder, in order to reduce tumor recurrence and reduce complications of cancer treatment to provide clinical thought process and feasibility.Methods1) A retrospective analysis from January 2010 to January 2013 at the Second Affiliated Hospital of Dalian Medical University, diagnosis and treatment of 970 cases of primary bladder cancer cases, according to the TNM staging of bladder cancer, elect Ta G1 to T1G3 period, and the line tur-bt surgery(transurethral resection of bladder tumor), and Pirarubicin 30 mg + 5% glucose solution, 30 m L, intravesical law. Subsequent recurrence and again the line of cases 41 cases tur-bt surgery. During chemotherapy, urinary tract ultrasonography line every three months to review, periodic review of blood, urine. Visit statistics patient age, gender, urine, bladder irritation, time to recurrence, complications case, within 12 months(including 12 months) were divided into a group of relapse, recurrence 12 months or more were divided into 2 groups for each possible related factors were analyzed. And provide a clear correlation between bladder irritation, then the existence of bladder irritation as the basis, divided into two groups, the analysisof the factors associated relationship. Attempts to explore the relationship between non-specific inflammation of the bladder tumor recurrence, and also analyze the specific relevant factors.2) The spss20.0 software program was used by statistical analysis software application, for possible related factors univariate analysis, due to the acquisition of data are non-normal distribution, so the use of rank-sum test as the main way for the factors of relevance tested. For which P <0.05 indicators, impact factor analysis using linear regression.Results41 cases included cases of bladder cancer recurrence within one year 16 cases, 25 cases more than one year recurrence. Once divided into two groups. Age and tumor recurrence between the two groups was not statistically significant time into(Z value =-1.083, P> 0.05); gender and tumor recurrence between the two groups was not statistically significant time into(= 0.96, P> 0.05); if there is fever and tumor recurrence between the two groups was not statistically significant time into(= 1.31, P> 0.05); urinary red blood cells and tumor recurrence between the two groups was not statistically significant time into(Z value =-1.420, P> 0.05); urine leukocytes and tumor recurrence between the two groups was not statistically significant time into(Z value =-2.050, P> 0.05); bladder irritation and tumor recurrence time is divided into two groups There was significant difference between(Z value =-2.892, P <0.05). To whether bladder irritation grouped into two groups. Age difference between the two groups based on whether bladder irritation into statistically significant(Z value =-2.289, P <0.05); the difference between the two groups in gender and bladder irritation into whether there was no statistical significance(= 0.593, P> 0.05); if there is fever and to whether the differences between the two groups into a bladder irritation was not statistically significant(= 0.427, P> 0.05); erythrocytes and urine of bladder irritation to whether there is divided between the two groups the difference was not statistically significant(Z value =-1.420, P> 0.05); and between the two groups of white blood cells in urine in the bladder irritation into whether there was nostatistically significant(Z value =-2.025, P> 0.05); the recurrence time and the difference between the two groups based on whether bladder irritation into statistically significant(Z value =-2.892, P <0.05).ConclusionBladder irritation and bladder tumor recurrence was significantly related to bladder irritation of the cases do not appear more than the median time to recurrence was significantly longer. Age, gender, and urine fever after chemotherapy in red and white blood cells and tumor recurrence were not related bladder irritation. Age and bladder irritation related to older, more prone to bladder irritation. Studies have shown irritation of the bladder tumor recurrence cases for a long time. Samples need to be expanded in the future. With large-scale randomized prospective studies and long-term follow-up to further validate, mining bladder irritation reason to delay tumor recurrence, which is very important to the prevention and treatment of clinical significance.