Study On Four-dimensional Echocardiography Of Left Ventricular Systolic Function In Patients With Essential Hypertension

Background:Hypertension is the most common cardiovascular disease, whichis the one of the major public health problem in the world. As theincreasing of the hypertension，it will change the function and thestructure of human’ s heart. In such condition that leadsArrhythmia, cardiac remodeling, heart failure, and even death.Therefore,early detection and correction of hypertension patientson left ventricular guidance has an important implications forfuture treatment and precention.Objective:Application of four-dimensional echocardiography in4-D AutoLeft Ventricular quantification (4D Auto LVQ) and four Dimensionalstrain technology changes in the assessment of Left Ventricularsystolic function in patients with hypertension.Material:Random samply for selecting65cases of patients with essential hypertension (eh) and20cases of healthy volunteers. Patientswith essential hypertension (eh) has regarded as left ventricularconfiguration (Ganau type). The left ventricular configuration is thenormal group (group A), which has got16cases.Then centripetalreconstruction group (group B) has got20cases. Nextiscentripetal hypertrophy group (C group), and there were15cases. Finally it the concentric hypertrophy group (group D), andthe group selected14cases.Methods:The application of GE Vivid E9, cardiac probe configuration M5Sand3V full volume is the main methords. Is has Instructed withclient to left side a quiet breathing, synchronous connectionelectrocardiogram (ecg), monitor of the subjects of real-timethree-dimensional echocardiography, inventory. The4d mode isthe environment for collectiong left ventricular mass andleftventricular EF value. In order to measure and compare these fourdimensional. Applied with strain value, color coding andthe bull’s-eye of figure show17section strain values. All data arecollected by using SPSS17.0software for analysis.Results:1The comparision of general data: heart rate (HR) hypertensiongroup and control group, the difference of the age, body surfacearea were not significant (P>0.05). Left ventricular mass index(LVMI) cases in each group were significantly higher than that ofcontrol group (P <0.05), and between the case group showed atrend of increasing; Ventricular septal thickness (IVSd), leftventricular posterior wall thickness (LVPWd), ventricular wall thickness (RWT) relatively higher in group B and C, and othergroups have significant difference (P <0.05), but there was nosignificant difference between B and C group (P>0.05). Leftventricular ejection fraction measurements only in group D wassignificantly lower than other groups (P <0.05).2The comparision of left ventricular total strain parameters: leftventricular hypertension group GLS, GCS, GAS are relativelylower than control, and showed A trend of decline, the area ofstrain in group A more sensitive than others. GRS in hypertensiongroup was first increases, then reduce the development process.3The comparision of left ventricular local strain parameters:application of four dimensional strain technology it is concludedthat the left ventricular segmental17local strain value,respectively, and the basal, middle section, apex section of theaverage strain values. Conclusion paragraphs average strainvalues, in the normal group in central middle section>apex>basaldepartment base. Poor regularity and hypertension group.Conclusion:1There are for dimension in normal left ventricularsegmental,whichhas certainly regular. as well as the middlesection> apex segment> basal segment. The results showshypertension patients was poor.2Hypertension patient first appeared cell damage under theendocardium myocardial condition. It means that the longitudinalstrain and the area of strain are damaged first, and radial strainincreased in the early days. The strain can reduce the longitudinalstrain, maintain the whole left ventricular systolic function. As refactoring degree aggravating gradually extends to left ventricularannulare hypertrophy, andrefactoring left ventricular high loadcan’t compensatory pressure. Then, left ventricular systolicfunction value is reduced obviously.3Area of strain as a two-dimensional strain parameterscombinesmyocardial longitudinal and circumferential direction movement.It is a new index for assessment of left ventricular function, and itmay be more sensitive, more early detection of abnormalhypertension patients with left ventricular systolic function.4The4D Auto LVQ and4d Strain technology can be moreaccurate evaluation for hypertension patients with differentconfigurations of left ventricular global and local systolicfunction.Early detection of HCM provides a new method fornoninvasive, which has great clinical application value.At the sametime it is also the development of conventionalechocardiography.