The Value Of Combined ABCD~2Score And Criminal Vascular Stenosis To Predict Stroke Risk After Transient Ischemic Attack

Objectives: To explore the predictive value of combined ABCD2and criminalvascular stenosis in evaluating brain infarction7days after the onset of transientischemic attack (TIA),and to compare the effectiveness of combined ABCD2andcriminal vascular stenosis with ABCD2score.Methods: The clinical data and imaging findings of67hospitalized by YijishanHospital of Wannan Medical College TIA patients from March.2012to Dec.2013wereanalyzed,and7-day follow-up of the cerebral of the patients were performed to look forrisks of infarction. According to ABCD2score, the patients were divided into threegroups:low risk group（0~3）,mid risk group（4~5） and high risk group（6~7）. Theincidence of stroke within7days after onset of TIA were compared among the threegroups.All the patients were scanned with brain magnetic resonance imaging to measurethe criminal artery based on clinical characteristics.According to the criminal arterystenosis rate,the patients were divided into two groups:≥50%group and <50%group.The incidence of stroke after onset of TIA were compared among the two groups.Meanwhile，the patients in the different groups of ABCD2score were respectivelydivided into≥50%group and＜50%group,to compare the incidence of cerebralinfarction. In this study, we added criminal artery stenosis to ABCD2score andseparated into low risk group（0~3）,mid risk group（4~6） and high risk group（7~9）.The predictive value of the two scores was evaluated by the area under receiveroperator characteristic curve. Results: Of67patients,18of them suffered cerebral infarction within7days afteronset of TIA.Grouped according to ABCD2score,10.0%patients had a stroke within7days in low risk group,35.5％had a stroke in mid risk group, and66.7％in high riskgroup.The incidence of cerebral infarction was different among the twogroups(P<0.05).The incidence of cerebral infarction was higher in≥50%group(44.4%) compared with <50%group (15.0%) within7days after TIA(P<0.05).Groupedaccording to ABCD2score combined with criminal artery stenosis,10.7%patients hada stroke within7days in low risk group,28.1％had a stroke in mid risk group, and85.7％in high risk group.The incidence of cerebral infarction within7days after onsetof TIA was different among the two groups(P<0.05).The area under the curve ofABCD2score combined with criminal artery stenosis for predicting the risk of cerebralinfarction within7days (0.763) was higher than ABCD2score at7days.(0.680).Conclusion:1.There was significant difference of the incidence of cerebral infarctionamong the three groups of ABCD2score.The incidence of cerebral infarction is highwhen the score is high.2.criminal artery stenosis≥50%is a risk factor for cerebral infarction after TIA.ABCD2score combined with criminal artery stenosis has a positive correlation withcerebral infarction after TIA.3.the incidence of cerebral infarction were significantly different among the threegroups of ABCD2score combined with criminal artery stenosis. ABCD2scorecombined with criminal artery stenosis could be used to assess the risk of stroke.4.The area under the ROC of ABCD2score combined with criminal artery stenosis wasgreater than that of ABCD2score.It was suggested that clinical value of ABCD2scorecombined with criminal artery stenosis was higher than ABCD2score.