A Study Of The Correlation Between Prognosis Of Transient Ischemic Attack With Cerebral Artery Atherosclerotic Stenosis

Objective To explore the correlation between the prognosis of transient ischemic attack with the characteristic of cerebral arteries stenosis and plaque.Methods Patients who came to the first affiliated hospital of Shanxi medicaluniversity with the final diagnosis of TIA for the first time attack. in2012.4-2013.7;Using the CTA to explore the stenosis extent of vascular, the set withvascular and the nature of plaques. Follow-up90d,daccording to the outcome can be divided into stable group,recurrent group and cerebral infarction group.Compare the three groups and find if there are difference among them.Results1.There are81cases bring into the experiment，stable group34cases （42.0%）,recurrent group37case（s45.7%）,and cerebral infarction group10cases（12.3%）.2. In stable group,there are24cases have vascular stenosis, in which have31stenosis postitions. In recurrent group,There are35cases have vascular stenosis, in which have65stenosis postitions. In cerebral infarction group,all of them have vascular stenosis,there are39stenosis postitions. In stable group,in which77.4%（24/31） mild stenosis,and16.1%（5/31） moderate stenosis,and3.2%（1/31）severe stenosis,and3.2%（1/31） occlusion.In recurrent group,in which73.9%（48/65） mild stenosis,and10.8%（7/65） moderate stenosis,and4.6%（3/65）severe stenosis,and10.8%（7/65） occlusion. In cerebral infarctiongroup,in which56.4%（22/39）mild stenosis,and10.3%（4/39）moderate stenosis,and15.4%（6/39）severe stenosis,and17.9%（7/39）occlusion.Among the three groups, with the increase of severity prognosis, severe stenosis and occlusi on are shown a gradual increasing tend,and mild stenosis will diminish. r=0.211, P=0.021,have statistical significance.3. In stable group,there are25cases have plaques, in which51.4%（18/35） calcific plaques,and34.3%（12/35）combined plaques,and14.3%（5/35）soft plaques.In recurrent group23.5%（12/51）calcific plaques,and47.1（24/51）combined plaques,and29.4%（15/51）soft plaques. In cerebral infarction group,in which12.9%(4/31) calcific plaques,and48.4%(15/31)combined plaques,and38.7%(12/31)soft plaques. Among the three groups,with the increase of severity prognosis,combined and soft plaques are shown a gradual increasing tend,and calcificplaques will diminish. r=0.364,P=0.001,have statistical significance.4. The EICA is the frequently stenosis in anterior circulation at stable group38.9%（7/18）,the ECVA is the frequently stenosis in posterior circulation at stable group38.5%（5/13）,the MCA is the frequently stenosis in aosterior circulation between recurrent group40.0%（16/40）and cerebral infarction group42.1%（8/19）,the ICVA is the frequently stenosis in posterior circulation between recurrent group36.0%（9/25）and cerebral infarction group35.0%（7/20）,and PCA35.0%（7/20）as same as ECVA in cerebral infarction.Conclusion:1. In this study the short time prognosis of TIA is associated with the stenosis degree of artery and nature of plaques. The severe stenosis and unstable plaque suggest with poor prognosis.2.The EICA is the frequently stenosis in anterior circulation at stable group,the ECVA is the frequently stenosis in posterior circulation at stable group,theMCA is the frequently stenosis in aosterior circulation between recurrent group and cerebral infarction group，the ICVA is the frequently stenosis in posterior circulation between recurrent group and cerebral infarction group.