| Background: With the popularity of screening in the worldwide, cervical cancer incidence dropped to thefourth in the position in women tumor. And the prevalence of cervical cancer in developing countries isstill in a high level, in China, for example, the prevalence of Xinjiang uygur women cervical cancer hasbeen high, and some of the poor rural areas of the Uighur settlements or even no data. The survey suggeststhat the rate of obesity among uygur women is high. Obesity can cause the body function disorder, chronicdisease even tumors. To perfect the national low income data in rural regions, probing into the cause of thehigh incidence of cervical cancer, this study set up in a typical uighurs in Xinjiang kashi area gathered oflow income in rural areas, focus on the region’s women cervical cancer prevalence, overweight and obesityprevalence and lipid metabolism related indicators.Methods: According to the exclusion criteria, the questionnaire survey used to record the basic information,the gynecological examination and pap smear used to know the cervical disease situation, taken biopsy forpathological examination when it was necessary. Measure the height and weight to calculate the mass index(BMI) and collect blood test main blood biochemical indexes. All data were entered to Epidata3.1softwaretwice to build a database, using SPSS17.0software for statistical analysis.Results: A total of the survey of1733women aged21to71,1452cases of data integrity. More than80%of the women’s day per capita income is$1or less. These low-income women for cervical disease situation,3900cases per100000for CIN1;960cases per100000for CIN2;340cases per100000for CIN3;200casesper100000for Cervical cancer. The average of body mass index (BMI) is24.0±4.0kg/m2.The prevalenceof overweight and obesity is as high as28.9%and15.1%respectively. Biochemical indicators of detection,this group of dyslipidemia rate is38.2%, high triglycerides (TG) rate was13.4%, high low-densitylipoprotein cholesterol (LDL-C) rate was5.4%, high total cholesterol (TC) rate of5.8%and low high-density lipoprotein cholesterol (HDL-C) rate of13.6%;Body mass index (BMI) was positively correlatedwith TG, LDL-C, TC, and negatively correlated with HDL–C. TG, TC and LDL-C in the cervicaldisease are differences in case group and control group (P <0.001), TG in high levels and HDL–C in lowlevels are cervix disease relative risk, respectively (OR=5.529, P <0.05; OR=0.420, P <0.01), the TCand LDL-C was positively correlated with the degree of cervical lesions (rs=0.398, P <0.01; rs=0.314, P<0.01). We have not find a direct relationship between BMI and cervical diseases.Conclusion: This area is a typical low income Muslim Uighur population, more than80%of their day’s percapita income at$1or less. Women surveyed the prevalence of cervical cancer and precancerous lesions,the prevalence of overweight and obesity were all higher. The BMI and some blood lipids has certainrelevance. Blood lipid in patients with cervical disease there is difference between two groups. Being Highlevels of TG and low levels of HDL-C may be suffering from a risk factor for cervical lesions. TC andLDL-C level and the progress of the cervical lesions were positively related.Suggestion: According to the results, we put forward some Suggestions for public health policy: first, inorganized large disease screening, it should be to put the BMI in, to monitor obesity so as to prevent theoccurrence of obesity related diseases; Secondly, in the poor areas recommended a economic and practicaltwo-step screening strategies: first of all to carry on the simple obesity (BMI) screening, further screeningin obesity crowd obesity-related diseases, especially diabetes and cardiovascular disease; Third, in theprocess of the treatment of cervical disease, the focus on lipid changes in obese women, may haveimplications for disease progression. |
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