Clinical Study On The Therapy Of PDS Of Spleen Deficiency And Dampness Type By Zhishixiaopi Tang

Objective and significance: This study makes observation of theclinical efficacy of the PDS （spleen deficiency and dampness type） thatis a subtype of FD as the starting point. The study compares Zhi Shi XiaoPi pill with Mosapride tablets in order to make clear the clinical curativeeffect of the symptoms. The study will provide the clinical evidence andliterature basis to the further research, development and application ofthe medicines that treat the type of disease.Methods:58cases of postprandial Distress Syndrome divided into twogroups. One was the observing group;28cases treated with ZhishixiaopiTang,the other was the control group:28cases treated with Mosapridetablets. Course of treatment was one month. Contrast the index of two sets,such as the total effective rate, total accumulated points of symptom,the improve of major clinical symptom and so on,as well as to make outthe judgment.Results:（1）The total curative effect of the observing group was96.43%; Thecontrol group was96.43%; The total curative effect had prominentdifferences （p＜0.05）, the observing group was superior to the controlgroup.（2）The observing group is superior to the control group in improvingthe curative effect and reducing the points of cardinal symptoms except the syndrome of Fullness after eating, two remarkable differences exist（p＜0.05）.（3） The end of treatment were followed up for6months to observethe relapse rate was24%,control group,the recurrence rate was60%,the twogroups was statistically significant difference in recurrence rate（P＜0.05），observe the long term efficacy than the control group．（4）These two groups had no obvious influence in blood, urine,evacuation of bowels, function of liver and kidney.Conclusion: The treatment based on Zhishixiaopi Tang, could obviouslyimprove the symptoms of Postprandial Distress Syndrome, the curativeeffect is superior to the control group.