Small Selection Of Traditional Chinese Medicine Compound On Renal Protective Effect Of Diabetic Nephropathy In Mice

Purpose: For this issue by studying experimentally observed small selection oftraditional Chinese medicine compound diabetic nephropathy in mice renal protective effecton impact, confirming Chinese medicine for the prevention and treatment of diabeticnephropathy have a good effect.Method: By intraperitoneal injection of streptozotocin (STZ),copy the model of diabetic nephropathy. Become the mice were divided into four groups ofmold, each10. A group of model group, without giving any treatment; other three groups bygavage doses of medicine divided into low, medium and high dose groups. While taking thesame batch of10rats with age and body weight of normal mice mouse modeling to match, asa control group. Using selective precipitation method, radioimmunoassay, reductase and othertechnical means to explore the impact of small compound medicine under the guidance of QiHuoxuetongluo law diabetic kidney function and kidney function kidney protection in mice,to verify that the small compound for diabetes Preliminary exploration control effect and itsmechanism of rat kidney disease.Result:1. Selection of traditional Chinese medicine caneffectively improve the indicators of renal function.2. Three groups of mice treated withtraditional Chinese medicine in the blood, kidney weight index were compared with thecontrol group of mice were improved DN, including traditional Chinese medicine dose effectis most significant.3. Three groups of mice treated with traditional Chinese medicine on theindicators of kidney tissue SOD and MDAand TNF-α levels and other more DN control micewere improved, including the efficacy of traditional Chinese medicine in the most significantdose group.Conclusion: The selection of Chinese small compound with prevention andtreatment of diabetic nephropathy.