Correlative Study Of MRI And Pathological Changes Of Lumbar Intervertebral Disc Degeneration

Objective To investigatet the consistency of magnetic resonance imaging(MRI) and pathological changes in reflecting lumbar intervertebral disc degeneration.Methods Thirty patients with lumbar intervertebral disc herniation who were given operative treatment in Orthopedics Department of the First Affiliated Hospital of Xinxiang Medical University from September 2013 to September 2014, were selected as experimental group. Twenty patients with lumbar intervertebral disc herniation who did not undergo operative treatment but with pain in waist and lower extremities were selected as control group. The average signal intensity of MRI for lumbar intervertebral disc was measured in the 50 patients. Nucleus pulposus specimens of surgery patients were collected during operation, water content of nucleus pulposus was analyzed after operation, chondroid cells were observed and counted under a microscope, the correlation between average signal intensity and water content nucleus pulposus with lumbar intervertebral disc herniation was statistical analyzed, the consistency of MRI and pathology of lumbar intervertebral disc degeneration was inspected. The degree of lumbar intervertebral disc herniation was evaluated by height measurement.Results The average signal intensity of control group was significantly higher than that of experimental group(P<0.01). Average signal intensity and water content of type Ⅱ intervertebral disc in experimental group were significantly higher than those of type Ⅲ intervertebral disc(P<0.01). Average signal intensity of type Ⅱ and type Ⅲ intervertebral disc in experimental group was positively correlated with water content (r=0.989、0.979, P<0.01). Chondroid cells of type Ⅱ intervertebral disc in experimental group was significantly higher than type Ⅲ intervertebral disc(P<0.01). K value of MRI and pathology which could reflect the lumbar intervertebral disc degeneration was 0.74, K values were 0.40～0.75, which illustrated that there was significant consistency between MRI and pathology in reflecting the lumbar intervertebral disc degeneration. Anterior height, posterior height, average height, specific value of anterior height and posterior height of L4-5 and L5S1 in control group were higher than those in experimental group(P<0.01).Conclusion MRI and pathology has significant consistency in reflecting lumbar intervertebral disc degeneration, which provides theory basis for clinical diagnosis and treatment of lumbar intervertebral disc herniation.