| Objective:through the collection and analysis of 22 cases of phlegm damp type PCOS complicated with hypothyroidism patients menstruation, personal information,physical examination,laboratory examination, four diagnostic methods of TCM and other related information,comprehensive study of famale patients,thyroid function in secretion and glucose and lipid metabolism,the characteristics of phlegm damp type ploycystic ovarian syndrome the possible factors and phlegmy wet type PCOS and therelationship between thyroid fuction hypothyroidism in women with polycystic ovary,for the treatment of PCOS,especially refractory PCOS to provide ideas and new approaches to treatment,with a certain amount of theoretical and practical significance.Methods:from2014 May-2015January were from the First Affiliated Hospital of Heilongjiang University Of Chinese Medicine gynecological clinic and in accordance with the diagnostic criteria of Western medicine andChinese medicine and the data of 22 cases of phlegm damp type polycystic ovarian syndrome complicated with hypothyroidism patient infoemation,including personal information,menstrual condition,physical examination and laboratory examination(including six sex hormones,five thyroid fuction,blood lipids,fasting glucose and fasting insulin),four diagnostic methods of TCM and other related information in the database,using descriptive statistical method to analyze,and draw a conclusion from the analysis resuts.Result:Test group:22 cases of phlegm damp type PCOS complicated with hypothyroidism patients;Control group:30 cases of phlegm damp type PCOS complicated with thyroid fuction was normal patients, the two groups were statistically analyzed using the statistical software SPSS 17.(1)two groups of BMI was compared and the result is no significant difference(P> 0.05);(2)the difference between acne and hirsutism and acanthosis nigricans,there was only the acanthosis nigricans had significant difference(P< 0.05);(3)compared two groups of E2,FSH,LH,LH/FSH,T and PRL level shows no significant difference(P> 0.05);(4)compared two groups of DHEAS, AND and SHBGlevel shows no significant difference(P> 0.05);(5)compared two groups of GLU,HDL-C,TG,LDL-C,TC, APOA and APOB level,there was no significant difference(P> 0.05); (6)compared two groups of INS and Home-IR,the difference was significant (P<0.05); (7)patinents with PCOS correlation analysis:TSH and LDL-C had positive correlation with TC(P<0.01), but no correnlation with T,E2,FSH,LH,LH/FSH,PRL,GLU,TG,TC,HDL-C and LDL-C(P> 0.05); (8)9 cases of hypothyroidism group menstruation amenorrhea in 8 cases,5 cases of uterine bleeding,thyoid fuction normal group of 14 cases of delayed menorrhea,amenorrhea in 12 cases.4 cases of uterins bleeding.ConclusionrThe change of thyoid fuction main influence the clinical expression though the insulin resistance and glucolipid menabolism,correlation analysis also prove TSH and LDL-C had positive correlation with TC,but the patient of the test was bit,so TSH and INS had not positive correlation with Home-IR in this test. |