The Study That Blood Stasis Is The Pathological Basis And Pathological Product Of The Osteoporosis

Objective:Demonstrated the correlation between blood stasis and osteoporosis, provide a basis forosteoporosis treatment using the way of clinical activating circulation to remove blood stasis.Method:Four hundred of cases which meet the Osteoporosis standard symptom of <Traditional Chinese medicine observation list> was collected from Xiyuan hospital of China academy of traditional Chinese medicine, for all of patients, detect bone mineral density and pulse wave conduction velocity(baPWV), score the blood stasis symptom, sublingual collaterals blood stasis, pain grade, and measure the fracture number. According to the data, analysis the correction between the parameters measured above with bone mass. Next-divided all the data of stasis syndrome score, sublingual collaterals blood stasis score, pain scores, baPWV, into two groups, the lower group and higher group, comparing bone mass between corresponding groups. According to syndrome differentiation of traditional Chinese medicine, the four hundred cases can be divided into two groups, blood stasis group and normal group, compare their blood mass, fracture number, pain score and pulse wave conduction velocity (baPWV).Result:There was a negative correlation between bone mass and blood stasis symptom score, sublingual collaterals blood stasis score, pain scores, baPWV and fracture number; bone mass show significantly differernce between higher group and lower group. Bone mass, fractures number, pain score, baPWV show obvious difference between blood stasis group and normal group.Conclusion:(1) Bone mineral density has negative correlation with blood stasis syndrome score, the higher the blood stasis syndrome score becomes, the lower the bone mineral density is.(2) Bone mineral density has negative correlation with sublingual collaterals score, the higher the sublingual collaterals score becomes, the lower the bone mineral density is.(3) Bone mineral density index has negative correlation with pain index, the higher pain index becomes, the lower bone mineral density is.(4) Bone mineral density has negative correlation with pulse wave conduction velocity, the faster the pulse wave transmission speed becomes, the lower the bone mineral density is.(5) Blood stasis group has a lower bone mineral density, higher incidence of fracture, higher pain index, faster baPWV than normal group.(6) Blood stasis not only lead to the pathogenesis of osteoporosis and is pathological product of osteoporosis.