The Initial Evaluation To The Rebleeding Risk Factors Of OGIB Patients After Capsule Endoscopy

Background and Objective Capsule endoscopy(CE) is currently accepted as the first-line diagnostic examination for clinical diagnosis of obscure gastrointestinal bleeding(OGIB) since 2000 because of its non-invasion, intuition, and high detection-rate. However the result of CE test is unable to predict whether the patient will rebleeding. The purpose of this study is to preliminary discuss the related risk factors of rebleeeding of the OGIB patients with positive or negative CE examination, and expect to reduce the rate of rebleeding.Methods We retrospectively analyzed 116 cases of patients with follow-up data who were selected by OGIB for CE examination in First Hospital Affiliated to Suzhou University from 2009 October to 2013 October. Collecting all inpatient medical records, and making the rebleeding as the primary endpoint in this study, using the single factor and multi-factor analysis to discuss the risk factors related to rebleeding.Results Ⅰ.The 116 patients were followed up for 12 to 57 months, and the median time is 36 months. 66 cases were positive in CE examination(56.90%), and the rate of rebleeding is 37.93%(44/116). 95.45%(42/44) of rebleeding cases occurred in 24 months after the CE examination. Ⅱ.The rate of rebleeding in CE positive-group(32 /66,48.48%) is higher than that in negative-group(12/50,24%)(P<0.01). Ⅲ. Patients who are 50 years or older, male, with a history of hypertension or had more than or equal to 500 ml cumulative amount of bleeding in 3 months before the CE test is four independent risk factors associated with the higher rate of rebleeding in the group of positive. Ⅳ.Patients who are 50 years of age or older, with abnormal blood coagulation or without specific treatment is the three independent risk factors associated with the higher rate of rebleeding in the group of negative.Conclusion Ⅰ.We should pay attention to identify OGIB patients’ risk factors of increasing rebleeding rate in clinical.Ⅱ. To high-risk patients, CE examination should be followed closely after at least 24 months. Ⅲ.The OGIB patients without risk factors can avoid duplication of inspection, in order to reduce the occurrence of related complications and medical resources waste.