Clinical Study Of Qiang Wu Analgesic Soup In The Treatment Of Wangbi(Rheumatoid Arthritis)Cold Damp Syndrome

Purpose: The purpose of the study was to evaluate the Qiang Wu Analgesic soup in the treatment of Wangbi(rheumatoid arthritis) cold damp syndrome clinical efficiency and safety.Method:Collected 60 cases of Wangbi(rheumatoid arthritis) of cold damp syndrome in patients, randomized single blind parallel controlled method, 30 patients given Qiang Wu Analgesic soup treatment as the treatment group, 30 patients given Han bi ting tablet treatment for the control group. After four weeks treatment, the statistical analysis was performed by the clinical symptoms, signs and laboratory indicators. Thus analysis of Qiang Wu Analgesic soup on the treatment of rheumatoid arthritis the clinical efficacy and safety of cold damp syndrome.Result:1, The influence on Chinese medicine symptom integral Two groups of patients after treatment of TCM syndrome score before treatment were significantly decreased, with significant difference(P < 0.01); Two groups of patients after treatment of TCM syndrome integral for analysis of statistics, there are significant differences between groups(P < 0.01). It follows two groups of treatment are effective, the treatment group is better than the control group.2, Affecting the efficacy of TCM syndrome Treatment group 30 cases, 0 cases cured, 2cases were markedly effective, effective 24 cases, 4 cases were invalid, the total effective rate was 86.67%. Control group 30 cases, cured 0 cases, 0 cases were markedly effective, effective16 cases, 14 cases ineffective, the total effective rate was 53.33%. By chi-square analysis,chi-square = 2.983, P = 0.003 < 0.01, there are significant difference, the treatment group is better than the control group.3 、The influence of TCM disease classification Treatment group after treatment of traditional Chinese medicine disease classification: 22 cases, mild to moderate 8 cases, severe0 cases; The control group after treatment of traditional Chinese medicine disease classification: mild in 2 cases, moderate 26 patients, and severe in 2 cases; The rank and inspection, Z = 5.243, P = 0.000 < 0.05, there are significant difference, the treatment group is better than the control group.4、The influence of swollen joints, tenderness of joints, Erythrocyte sedimentation rate,C-reaction Protein, Rheumatoid factor, anti-cyclic citrullinated peptide antibody Between two groups of patients after treatment group statistical analysis, swollen joints, tender joints and C-reactive protein was significant difference(P <0.05), ESR, rheumatoid factor and anti-cyclic citrullinated peptide antibody was not statistically significant(P> 0.05);After treatment, patients in the group statistical analysis, swollen joints, tender joints, ESR and C-reactive protein was significant difference(P <0.05), rheumatoid factor and anti-cyclic citrullinated peptide antibody was not statistically significant(P> 0.05).5、The impact on the DAS28 By means of two groups of patients before and after treatment of DAS28 group statistical analysis, two groups have significant difference(P <0.01). DAS28 contrast analysis of two groups of patients after treatment, there was no significant difference(P > 0.05). Treatment group after treatment DAS28 efficacy: invalid 3cases, 6 cases effective, 21 cases were markedly improved; The control group after treatment DAS28 efficacy: invalid 8 cases, 15 cases, 7 cases; The rank and inspection, Z = 3.392, P =0.001 < 0.05, there are significant differences. It can be thought of as two groups of treatment to reduce DAS28 all have significant difference, but the treatment group is better than the control group.6、Evaluation of the impact of the two ACR Treatment group: ACR20 have 19 cases,ACR50 have 2 cases, ACR70 have 0, < ACR20 have 9 cases, the total effective rate was70.00%. Control group: ACR20 in 13 cases, ACR50 have 0 cases, ACR70 have 0, < ACR20 in 17 cases, the total effective rate was 43.33%. The rank and inspection: Z = 2.245, P = 0.025< 0.05, the reason to think that there are significant differences, treatment group curative effect is better than the control group.7、Drug Safety Observation Before and after treatment, two groups of 60 patients did not experience symptoms such as diarrhea, dizziness, headache, rash, does not appear blood routine, urine routine, stool routine, liver function, renal function and electrocardiogram abnormalities.Conclusion:Qiang Wu Analgesic Soup therapy Wangbi(rheumatoid arthritis) Cold Damp Syndrome can reduce ESR, C-reactive protein and TCM symptom scores, reduce the number of swollen joints and tender joint. In the lower C-reactive protein and TCM symptomscores, reduce the number of swollen joints and tender joints, DAS28 efficacy aspects of ACR evaluation and its efficacy is superior han bi ting tablets group;Qiang Wu Analgesic Soup medication safety, no adverse reactions, should be promoted for the development of hospital preparations provide an objective basis.