Danloupian Treatment Of Phlegm And Blood Stasis Resistance Type Complex Clinical Study Of Unstable Angina

Purpose:This research belongs to Chinese medicine research field of cardiovascular medicine. By Dan loupian clinical research in the treatment of phlegm network type unstable angina, verify Integrative Medicine phlegm network type of unstable angina clinical efficacy and safety, thus providing a new treatment for unstable angina the ideas and methods.Method: The clinical observation of all patients were randomly divided into two groups, the treatment group and the control group of 30 patients, a total of 60 cases. Western medicine treatment group on the basis of the standard treatment plus Dan loupian piece, the control group was simply Salvia Dan loupian Western standardized medication placebo tablets. Respectively, before the test and test four weeks of the end of the event record, angina pectoris, angina classification, MMP-9, PAPP-A indicators and statistical data analysis using statistical software SPSS13.0.Result: In this study, two groups of sudden death did not occur, the treatment group had one case of non-fatal myocardial infarction, hospitalization events, there are two cases in the control group of non-fatal myocardial infarction, hospitalization events, the treatment group had one patient during the test implementation of acute revascularization events in the control group had two cases during the trial implementation of revascularization, although no statistical test groups was statistically significant, but only from the number of cases occurred, the treatment group than the control groups.Angina therapy: Dan Trichosanthis sheet plus efficiency was 86.7%, effective conventional Western medicine was 70%, the statistical analysis, the two groups although no statistical significance, but the efficiency of the comparison can be seen in the treatment group than in the control group. Angina attacks, duration of epilepsy, angina grading outcome measures at the end of treatment were statistically significant(p<0.05) between the two groups, the treatment group than the control group. The angina pain score between the two groups after the end of treatment was not statistically significant, but before and after treatment were statistically significant(p<0.05).Objective indicators of improvements, MMP-9, PAPP-A values were significantly better than the improvement of the control group.Conclusion: Dan loupian western medicine tablets with unstable angina pectoris(phlegm network card), efficacy in angina symptoms, angina grade the degree of improvement, MMP-9, PAPP-A indicators are better than western Salvia loupian piece comfort agent group, said Mingdan loupian piece in improving phlegm network of angina pectoris in patients with clinical symptoms, inhibiting the inflammatory response, and stable plaque and antioxidant role has a certain effect.