The Clinical Analysis About The Relationship Between IBS And Psychogeny

Objective:explore the relationship between irritable bowel syndrome (IBS) and mental disorders (mainly the anxiety and depression), to provide objective basis for guiding the treatment of patients with IBS and preventing recurrence.Methods:The experimental group was comprise of 112 patients with IBS, who fulfilled the exclusion and internalize standard from June 2012 to December 2013 in digest division of HuaShan hospital, the control group was comprise of 103 non-IBS people with the same exclusion and internalize standard. Investigate their general state of health and evaluate them by Hamilton anxiety rating scale (HAMA) and Hamilton depression rating scale (HAMD). According to HAMA/HAMD scores determine anxiety and depression. HAMA scale score of 7 or higher may have anxiety symptoms,14 part must have anxiety symptoms, or greater than or equal to 21 must have obvious anxiety, or specific provisions of 29 must have severe anxiety; Specific provisions of HAMD scale score of 8 or higher may have depression, specific provisions of 20 or higher may be mild or moderate depression,35 specific provisions or higher may be severe depression. (1) comparing with IBS group and control group in the incidence of anxiety and depression, and two groups of HAMA and HAMD rating scale; (2) according to the patients with IBS HAMA and HAMD scores respectively to transform its companion anxiety and depression (HAMA score 7 points, HAMD scores or eight points or higher) and no anxiety and depression (HAMA score< 7 points, HAMD score< 8) of the binary classification should be variable to the discretion of the age, gender, educational level, whether comorbid chronic disease, the course length of IBS, and long-term medication as the independent variable on the single factor analysis of the history and based on the statistics of uplink multiple factors analysis; (3) comparing elderly IBS group (age 60 or higher) and young and middle-aged IBS group (18 years old or less age <60 years old) the incidence of anxiety and depression as well as the scores of the two groups of HAMA and HAMD scale; (4) comparing elderly IBS (age 60 or higher) in the group with chronic diseases, including hypertension, type 2 diabetes, coronary heart disease (CHD) of one or more) between the group and not associated with chronic disease incidence of anxiety, depression, and two groups of HAMA and HAMD scale score; comparing the incidence of anxiety or depression between the elderly IBS group (age 60 or higher) and young and middle-aged IBS group (more than 18 years old and less than 60 years old), and two groups of HAMA and HAMD rating scale; (5) analysis of relatively young and middle-aged IBS (18 years old or less age< 60 years old) in the group with chronic diseases, including hypertension, type 2 diabetes, coronary heart disease (CHD) of one or more than one) between the group and not associated with chronic disease incidence of anxiety, depression, and two groups of HAMA and HAMD scale score.Results:(1) IBS group anxiety (including HAMA scale score 7 or higher group and the group of 14 or higher) and depression (HAMD scale score of 8 or higher grouping and 20 groups or higher) and the incidence of HAMA and HAMD scale score were higher than in the IBS group, the difference was statistically significant (P<0.05); The IBS group anxiety (HAMA scale score of 21 groups) or the incidence is higher than the IBS group, but there was no statistically significant difference (P>0.05); (2) by the single factor analysis, the influencing factors of IBS patients with anxiety, depression, happen to culture level of high and low, are associated with chronic disease, and the course length of IBS, the difference was statistically significant (P< 0.01); And has nothing to do with age, gender, history of medicine for a long time, there was no statistically significant difference (P>0.05); (3) the multiple factors analysis, the factors influencing the anxiety and depression of IBS patients with type 2 diabetes and coronary heart disease, the course length of IBS and cultural level, the difference was statistically significant (OR>1, P<0.05); And has nothing to do with associated with hypertension, there was no statistically significant difference (P> 0.05); (4) anxiety IBS group (including HAMA scale score 7 or higher group and the group of 14 or higher) and depression (HAMD scale score of 8 group) or the incidence were higher than in young and middle-aged IBS group, but there was no statistically significant difference (P>0.05); While young and middle-aged IBS group depression (HAMD scale score of 20 groups) or the incidence is higher than the old IBS group, the difference was statistically significant (P<0.01); (5) the old IBS HAMA scores higher than that of young and middle-aged IBS group, but there was no statistically significant difference (P>0.05); Young and middle-aged IBS HAMD scores higher than the old IBS group, there is no statistically significant difference (P>0.05); (6) IBS elderly with chronic disease group anxiety (including HAMA scale score 7 or higher group and the group of 14 or higher) and depression (HAMD scale score of 8 group) the incidence were higher than without chronic disease group, the difference was statistically significant (P<0.05); IBS elderly with chronic disease group of depression (HAMD scale score of 20 group) or above is not associated with chronic disease incidence group, but differences had no statistical significance (P> 0.05); (7) the young and middle-aged IBS with anxious chronic disease group (including HAMA scale score 7 or higher group and the group of 14 or higher) and depression (HAMD scale score of 8 or higher group and 20 or more group) and the incidence of HAMA and HAMD scale score were higher than without chronic diseases group, differences were statistically significant (P<0.05).Conclusion:IBS patients with mental disorder (mainly anxiety and depression) the incidence of a healthy population is high. The cultural degree is high, long IBS fixed number of year of the course of the disease and associated with chronic systemic disease (especially with type 2 diabetes and coronary heart disease) patients with IBS, the mental disorder (mainly anxiety, depression) might have a higher incidence of. So the IBS patients should be given appropriate psychological assessment and treatment, in order to improve the clinical curative effect, improve the disease outcome, so as to improve the quality of life of patients.