| Objective:To evaluate the safety and efficacy of green-light lithium triboride (LBO) laser resection for primary non-muscle-invasive bladder tumors (GLRBT) compared with transurethral electroresection of bladder tumor (TURBT).Methods:From November 2012 to August 2014, a total of 163 consecutive patients with primary non-muscle invasive bladder tumor were treated by green-light LBO laser resection (GLRBT group, n=85) or transurethral electroresection (TURBT group, n =78), retrospectively. The preoperative, intraoperative and postoperative clinical characteristics were recorded and compared in the two groups. The recurrence-free survival for 24 months in the overall group was analyzed and compared.Results:There were no differences with the preoperative characteristics between the patients in two groups. The mean operative time was 24.2±2.4 minutes for GLRBT and 29.7±2.4 minutes for TURBT (P<0.001). Obturator nerve reflection was absent during GLRBT, whereas it was observed in 6 patients during TURBT.2 patients in TURBT group and 1 patient in GLRBT group suffered bladder perforation. Only 1 patient in TURBT group experienced urethral stricture, while none in GLRBT group. A significant difference in favor of GLRBT was achieved for the postoperative catheterization time (2.83±0.96 days vs 3.19±0.91 days, P=0.016). The postoperative hospitalization time showed no significant difference in the two groups. The recurrence-free survival rate did not differ between two groups after 24 months follow-up, by Kaplan-Meier survival curves of recurrence time (P=0.437).Conclusions:The results of our trial have shown that GLRBT is feasible, safe, and effective alternative for the treatment of primary non-muscle-invasive bladder tumors, with fewer perioperative complications and similar rate of recurrence. Besides, it can provide intact specimen for the pathologic diagnosis, especially the accurate evaluation of tumor stage to predict postoperative prognosis. |
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