| Objective Osteoporosis a kind of metabolic bone disease caused by a variety of reasons, calcium salt and substrate of normal proportion, bone tissue with normal calcification, the characteristics of bone microstructure damage and per unit volume with low bone mass,which was the common and frequently-occurring disease and was becoming a serious problem threatening the elderly health through all over the world.The patients of OP were easy to fracture, disabled becausing of increased osteopsathyrosis, which could lead to serious social and economic problems. So early diagnosis, treatment and prevention of the OP had become more and more attented problem of the society. The World Health Organization(WHO) was classified osteoporosis basing on Bone mineral density(BMD), The normal standard was peak bone mineral density of healthy adults added and subtract a normal standard deviation, lower than the normal standard deviation(1 ~ 2.5) was bone loss, lower than 2.5 standard deviations was osteoporosis, lower than more than 2.5 standard deviations and with one and more brittle fracture was severe osteoporosis. This study provide clinical data for the prevention of OP by measuring the BMD of normal people in hefei area, and the lifestyle questionnaire investigation which may lead to the OP.Methods To collect included in the standard of 1378 cases in hefei area from September 2012 to January 2015 in Anhui province hospital check-up. Participants, age ranged from 20 to 79, include 752 female, 626 male, according to 5 years old age one group. The BMD of forearm, proximal femur, L2-4 were measured by Lunar Plus dual energy X-ray absorptiometry and then uses the questionnaire survey method under guidance of physician about their general situation, lifestyle including smoking, diet habit, drinking,exercise and light duration, which were also investigated and graded. The relationship between life style and BMD was analyzed. The experimental results were analysed by the SPSS17.0 statistical software.Results1.The BMD of male was decreased with age when it reach peak, and had no obvious decline with age. While that of female The BMD was sharply decreased after 50 years old in female when it reach peak. The bone peak of forearm was 35 to 39 years old, the bone peak of proximal femur was 25 to 29 years old,femoral neck bone, the bone peak of L2-4 was 30 to 34 years old.2. The cumulative loss of BMD was femoral > forearm >lumbar3. The incidence of OP was increased with age after 50 years old. The incidence of OP was higher in female than male in all ages4. The BMD in the region had a downward trend5.Multiple linear regression analysis: the analysis of the BMD of femoral neck values and lifestyle survey found : the model of the determination coefficient R2 = 0.884, The BMD was correlated with usual halophilic quantity diet(P<0.01), usual amount of exercise,gender, light duration and smoking(P<0.05),but there was no significant correlation with drinkingConclusion1. The incidence of BMD and OP in hefei area had obvious gender differences, the BMD was significantly higher in male than female, the incidence of OP was higher in female than male2. The BMD of was decreased with age when it reach peak in both male and female, while the BMD of female was sharply reduced after 50 years old3. The BMD and bone peak are falling in recent 10 years of Hefei region, the OP prevalence has a rising trend4.Lifestyle has a certain influence on OP, especially high salt diet, lack of exercise and illumination time, excessive drinking and smoking... |
PDF Full Text Request