Clinical Features Of Young Patients With Acute Myocardial Infarction

Background:Acute myocardial infarction (AMI) in coronary heart disease (CHD) in critical condition, acute onset, rapid progress,as the death cause of CHD. In recent years, the incidence of AMI increased significantly, but the incidence tends to be younger, the age of onset decreased gradually. AMI in coronary atherosclerosis is the main pathological basis,risk factors, including traditional hypertension, diabetes, hyperlipidemia and smoking associated with AMI has been very clear, but in the young and more younger patients (aged ≤45 years) with AMI of the incidence is not well known. Along with the age of onset decreased gradually, there may be differences in rate of occurrenceof these traditional risk factors.Objective:Study on the analysis of the clinical features of young patients with AMI.Methods:Retrospective analysis of the clinical data and the characteristics of coronary angiography of January 2011 to December 2013 in the first hospital of Lanzhou University, for 153 coronary angiography in young patients with AMI; And the 153 patients were divided into aged ≤35 years and aged <35 years two groups, two groups of patients with clinical data, coronary angiographic characteristics were compared and analysis.Results:(1) A total of 153 patients met the inclusion criteria, the average age is 40.6±4.4 years old, including 142 male cases(92.8%),11 cases were female (7.2%); The most common is the hyperlipidemia (54.2%) and smoking (74.5%) in the traditional risk factors, among them the male smoking rate 80.3%; ST segment elevation myocardial infarction(STEMI) accounted for an absolute majority(93.5%). (2) Coronary angiography showed that 22.9% of the patients have intracoronary thrombus,22.9% of which are not associated with atherosclerotic stenosis. (3) In young patients with AMI, aged ≤35 years group compared with the aged<35 years group, aged ≤35 years group had higher levels of low density lipoprotein cholesterol, Obesity and family history of coronary heart disease proportion is higher. (4) Coronary angiography showed in young patients with AMI, Double-vessel lesion and three-vessel lesions in aged ≤35 years group were less than that aged <35 years group, coronary thrombosis incidence is higher in aged ≤35 years group.Conclusion:The main risk factors include smoking and hyperlipidemia in young patients with AMI. The smoking rates with age of onset younger still higher (aged ≤35 years), Obesity and family history of coronary heart disease is more prominent in the risk factors, And coronary angiography showed a higher incidence of coronary artery thrombosis. The certain proportion are not associated with atherosclerotic stenosis, This kind of young patients with AMI may be the primary coagulation disorders caused by thrombotic events, May be independent of atherosclerosis based.