Oolong Tea Drinkers With Gastric Mucosa Intraepithelial Neoplasia In TCM Syndrome Distribution Characteristics And The Change Of GAS And EGF

Objective:The investigation of TCM syndrome type distribution characteristics and the detection of GAS and EGF in the crowd of GIN patients who are oolong tea addicts discovered that the patiens attected by GIN about the TCM syndrome type distribution as well as the secrection of GAS and EGF.So it provide a reference for the prophylaxis and treatment about GIN in aspect of combination of Chinese and western.It may be clear whether oolong tea has the prevention function to GIN and lead peple live a correct lifestyle.Methods:Select 101 patients with GIN of meeting the conditions. According to its dringking tea situation into drink oolong tea and don’t drink tea two group.Among them 47 cases from drinking oolong tea group, the other 54 cases from don’t drink tea group. Besides,select 15 normal controls.According to standard of TCM syndrome types dialectic.Then place the gastric mucosa from gastric antrum one send to the pathological,cne test detection of HP infection with the rapid urease, and the last one obtained by gastroscope in the save liquid,-80℃ refrigerator saved.On the basis of the RT-PCR detection method was developed for the determination of EGF, GAS mRNA expression quantity relatively.Finally using statistical method to compare TCM syndrome types and the relative amount of mRNA expression of EGF, GAS between the drink oolong tea and don’t drink tea two group. As well as the major type of syndromes with EGF, GAS should be compared, and compared with the normalcontrols.Result:①In the HP infection rates,don’t drink tea group higher than drink oolong tea group (P<0.05).It suggusts that drinking tea can improve HP infection rates.②The above two groups compared to the TCM syndrome type distribution difference obvious(P<0.05).③Don’t drink tea set is given priority to the damp heat in spleen and stomach team,however,drink oolong tea set tend to spleen-stomach deficiency.④Compared with don’t drink oolong tea set, the drink oolong tea group is less inGAS EGF expression(P<0.05). ⑤Compared with the spleen-stomach deficiency and the stomach Yin deficiency syndrome, the damp heat in spleen and stomach team GAS EGFmRNA is higher in don’t drink tea group(P<0.05).⑥In the drink oolong tea set,the damp heat in spleen and stomach team EGFmRNA expression is higher than the spleen-stomach deficiency(P<0.05).The damp heat in spleen and stomach team and the stomach Yin deficiency syndrome and the spleen-stomach deficiency compare with eath other in GASmRNA expression is no obvious difference in drink oolong tea group.⑦Don’t drink tea to drink Oolong tea group there is no statistically significant differences in GIN extent(P>0.05). ⑧In the damp heat in spleen and stomach team the drink oolong tea EGF GASmRNA expression is lower than don’t drink tea group(P<0.05).⑨In the spleen-stomach deficiency team and the stomach Yin deficiency syndrome the drink oolong tea EGF GASmRNA expression is little lower than don’t drink tea group(P>0.05).Conclusions:Drinking oolong tea has effect on TCM syndromn type distribution and theGAS and EGF expression in patients with GIN.Oolong tea is fit for most of the crowd except the spleen-stomach deficiency people.Drinking oolong tea may slow down the progress of the GIN.GIN trouble patients need to pay attention to vary from person to person when choosing to drink oolong tea for prevention and cure.The spleen-stomach deficiency people with GIN should reduce oolong tea drinking even don’t drink oolong tea.The others can more appropriately drink Oolong tea.