| Background Our country has stepped into the aged society. The last sixth countryside census date published shows that, the number of sixty years take more than thirteen percents. As the population is getting astogeny, the morbidity of the elderly primary hypertensive patients in our country will increase. Hypertension is the leading risk factor to cause the cardiovascular and cerebrovascular events. It is also the grave public health all over the world. Because of their particularity, they often go with the other disease or the cardiovascular risk factors such as dyslipidemia and diabetes. The more risk factors they go with, the more harm they will do to the cardiovascular system. Recently the blood pressure variability has been extensively concerned by the academic of angiocarpy. The guide of china hypertension in2010has put forward it as the new basis of target spot.Objective To analyze the clinical character of BPV and its important meaning to the cardiovascular and cerebrovascular events in elderly primary hypertensive patients.Methods To choose sixty-eight elderly primary hypertensive patients and monitor the twenty-four hours of ambulatory blood pressure. To analyze the value of CV and the value of blood pressure of variability. The elderly hypertensive group was further divided into high BPV group (n=34) and low BPV group (n=34) according to the50th CV percentile of the variability of24hSBP,24hDBP, dSBP, dDBP, nSBP, nDBP. The clinical biochemistry index and the cardiovascular and cerebrovascular events were retrospective analyzed between the two groups in the three times. Analysis the influence of each index to blood pressure variability by statistical method.Results To24hSBPV in elderly hypertensive patients, the probability of the cardiovascular and cerebrovascular events is evidently bigger in high CV group than in the low one (p<0.05). But to24hDBP,dSBP,dDBP,nSBP,and nDBP,the probability of the cardiovascular and cerebrovascular events have no statistical difference (P> 0.05). To24hSBP,dSBP and dDBP in elderly hypertensive patients,the values of TG in high CV group are evidently higher than those in low CV group (P<0.05).To24hDBP,dSBP and dDBP in elderly hypertensive patients,the values of TC are evidently higher in high CV group than in low one (P<0.05). To dSBP in elderly hypertensive patients,the values of LDL-C are evidently higher in high CV group than in low one (P<0.05). The further correlation analysis shows that BPV of24hDBP,dSBP,dDBP in elderly hypertensive patients is in positive correlation with the value of TC (P<0.05).Conclusion BPV has a significant clinical meaning to the elderly primary hypertensive patients in occuring the cardiovascular and cerebrovascular events. High TC may lead to a high BPV. The difference in CV is not in interrelated with ages and primary diseases in the elderly primary hypertensive patients.We should pay attention to their BPV and interfere actively. |
