Factor Analysis For HPV Infection Of Uyghur Women In Moyu County Of Hotan Region Of Xinjiang

Objective:To investigate the current status of the Human Papilloma Virus (HPV) infection and the infection factors within rural Uyghur women in Moyu County, Hotan Region and to provide theoretical basis and guidance for the cervical cancer prevention in Xinjiang.Methodology:A survey on HPV testing and HPV infection factors was conducted on a total of5000Uyghur women with sexual activities aged21to60in Moyu, Dakar, Kuiya, Ayman al and Yawa of Moyu County, Hotan region, between June15and September15,2003. Survey questions include basic information, obstetrical history, sexual activities, personal hygiene situation, menstrual history, contraceptive history, as well as the characteristics of the spouse. Specimens were collected by two gynecologists and positive careHPV testing result was utilized to determine HPV infection. EpiData was used to process raw data. Statistical analysis was conducted using SPSS18.0. Chi-square test was used to test the differences in HPV infection rate and multivariate dichotomous logistic regression analysis was conducted to evaluate the effects of different risk factors. Statistical significance was determined by P<0.05.Results:A total of5000valid questionnaire copies was considered in the study. The population overall infection rate was8.4%. Chi-square test result suggests that HPV infection correlate with age (*2=22.529P=0.002), marital status (x2=13.970P=0.001), occupation (x2=21.157P＜0.001), occupation of spouse (x2=13.034P＜0.001), level of education (x2=36.175P＜0.001) as well as the level of education of the spouse(x2=21.457P＜0.001), annual household income (x2=11.621P=0.009), contraception situation (x2=8.154P=0.017), contraception measures (x2=37.181P<0.001), age when getting married (x2=20.360P<0.001), number of marriages (x2=11.605P=0.003), number of sexual activities (X2=60.126P<0.001), menstrual sanitary products (x2=67.182P<0.001), as well as toiletry products (x2=71.274P＜0.001). These factors are then incorporated into the multivariate logistic regression framework with stepwise selection where the variable is selected when α=0.05and eliminated when α=0.10. Regression analysis shows that age, marital status, occupation, frequency of sexual activities, menstrual sanitary products, toiletry products, whether contraception and different contraception measures are found correlated with HPV infection and are statistically significant (P<0.05).Conclusion:HPV infection among rural Uyghur women in Hotan region of Xinjiang is found correlated with age, marital status, occupation, frequency of sexual activities, menstrual sanitary products, toiletry products, whether contraception and different contraception measures. Measures should be taken targeted at the high risk factors. This suggests us that the sexual behavior of the population needs to be regulated and that the screening of menopause women, in particular aged45and above, should be conducted and monitored closely.