The Clinical Study On Replenishing Qi And Warming Yang, Tonifying Kidney To Holding Qi In Treating The Remission Stage Of Chronic Cor Pulmonale

Objective:Through the clinical research of chronic pulmonary heart disease in remission period (Yang deficiencies of the heart and lung, deficiency of the kidney and failing to hold Qi), sum up instructor’s treatment experience of replenishing Qi and warming Yang, tonifying the kidney to holding Qi with large dose of astragalus membranaceus for this disease. Evaluate the clinical effect of the above-mentioned treatment. To further explore chronic cor pulmonale effective treatment of traditional Chinese medicine lay the foundation,and in order to reveal the advantages of TCM in chronic cor pulmonaleMethod:From the diagnosis of chronic cor pulmonale in remission stage,we choose60patients of "Yang deficiencies of the heart and lung, deficiency of the kidney and failing to hold Qi", and randomly divide into two groups, treatment group and control group are30cases respectively.The treatment group:with decoction of replenishing Qi and warming Yang, tonifying kidney to holding Qi on the basis of the control group(codonopsis pilosula, cruded astragalus membranaceus60g, radix aconiti lateralis preparata, radix rehmanniae, cornus officinalis, chinese yam, schisandra chinensis, atractylodes, salvia miltiorrhiza,etc.), and adjuste treatment under the guidance of the principle of syndrome differentiation. The control group:adopt low flow inhale oxygen, antispasmodic, expectorant(aminophylline0.1g rid po, ambroxol30mg tid po, Si Lihua18ug qd indrawing), and with anti-asthma, strong heart, diuresis therapy according to patients’specific conditions.The clinical symptoms, CAT scores, the times of acute exacerbation,6minutes walking distance,and lung function of2groups were compared before and after treatment.Results:The treatment group’s total effective rate is90.0%, the control group is63.3%,the two groups’ total effective rate has significant difference (P<0.05). In the aspect of improving the main symptoms, the treatment group was better than the control group (P<0.01); in the aspect of improving the quality of life, the treatment group was better than the control group (P<0.01); after treatment,compared with the control group, the treatment group’s6min walking distance increased significantly (P<0.01), the times of acute exacerbation was significantly reduced (P<0.05); the lung function of two groups after treatment had no obvious improvement than before(P>0.05), after treatment,the decrease figure of FEV],FEVi/FVC treatment group were less than that of the control group, the differences were significantly different (P<0.05).Conclusions:The therapy of replenishing Qi and warming Yang, tonifying kidney to holding Qi for chronic cor pulmonale in remission stage has obvious curative effect,can relieve patients’symptoms, improve the quality of life, increase the amount of exercise,reduce the times of acute exacerbation,and can delay the lung function to further deteriorate in a certain extent...