Comparative Study Of The Clinical Characteristics Of Primary Nephrotic Syndrome In Children Between The Uygur And Han Children:a Single Center Report

Objective:To summarize the Uygur and Han primary nephrotic syndrome (PNS) clinical characteristics in children with onset. Methods:Retrospective analysis the clinical data of92cases of Uygur and Han patients diagnosed PNS in2011January-2013December who were primary and after regular follow-up in our hospital. Results:92cases of55patients of Uygur, male36cases, female19cases, mean age (5.72±3.60) years;37patients of Han nationality, male23cases, female14cases, mean age (6.32±4.22) years old, there is no significant difference between the two groups (P>0.05). Children are more concentrated in southern Xinjiang Uygur, Han children and more concentrated in the northern Xinjiang, is a significant difference between the two groups (P<0.001). Compared with the Han nationality children, children with HLDL, the level of ApoAI of Uygur is lower than Han patients (P<0.001), while CHO, TQ LDL, ApoB, lipoprotein (a) no significant difference between the level of children with Han (P>0.05); Uygur children in platelet levels higher than Han nationality (P<0.05), and the level of fibrinogen and D-two significant difference level there is no body of poly (P>0.05). There was no difference in proportion of Uygur and Han children in patients with onset of infection, but the children than the Han Uygur children more susceptible to infection (P<0.05). Complete remission in children with steroid resistant nephrotic and on the use of different immunosuppressive therapy for the final rate and partial remission rate did not differ significantly (P>0.05). Conclusion:the Uygur PNS patients and Han children in the same basic characteristics of the disease, but in children living in the area of the ratio of SRNS, and some laboratory indexes are different, the reason is still needed further study; primary nephrotic syndrome in children as long as they can adhere to the treatment of follow-up, most can achieve ideal treatment effect; at present not that there were genetic differences between Uygur and Han children in the pathogenesis of.