Hearing Function Evaluated Via DPOAE And ABR In Uyghur Patients With OSAHS In Xinjiang

Objective:To investigate whether OSAHS affects auditory pathway and corresponding characteristics in Xinjiang Uyghur nationality. Methods:The study population, including70Uyghur adults with OSAHS and35healthy Uyghur adults as control group, were monitored and diagnosed by polysomnography. According to data obtained, subjects were grouped into mild, moderate and severe degrees, respectively. After DPOAE and ABR detections, the effects of hearing pathway damage were evaluated. Results:The values of distortion-product otoacoustic emissions (DPOAEs), range from750Hz to8000Hz, were significantly decreased (P<0.05). By ABR tests, mild-to-moderate OSAHS group compared with controls, wave Ⅰ,Ⅲ,Ⅴ latency and interpeak latency Ⅰ-Ⅲ, Ⅰ-Ⅴ prolonged and difference with statistical significance (P<0.05), the severe group of ABR between different wave latency and wave interpeak period were significantly longer than control group (P<0.05), severe group compared with mild-to-moderate one, wave Ⅰ,Ⅲ latency and interpeak latency Ⅰ, Ⅴ has statistical significance (P<0.05).BMI, the obstructive site, snoring index, lowest oxygen saturation, DPOAE detected rate, ABR test results are closely related to the degrees of OSAHS.Conclusion:OSAHS has damage to the auditory pathway in Uyghur nationality, especially cochlear actively hearing function reduced obviously, at the same time with auditory nerve central section and the auditory center damage. Therefore, it should be early intervention treated, to prevent hearing complication.