The Clinical Study Is About The Research Of Efficacy For Treating Functional Dyspepsia(FD) Of Spleen Deficiency And Qi Stagnation With Su Medicine No.3

Purpose:In this study,through literature review on the theory of traditional Chinese medicine and Western medicine in treatment of functional dyspepsia were.Clinical study with randomized controlled trials,to improve the situation of Su medicine3prescription on the syndrome of spleen deficiency and qi stagnation type in patients with functional dyspepsia TCM syndrome,TCM symptomatology.threshold amount of drinking water,enough water quantity index,to evaluate the feasibility of its theoretical value in treatment of this disease and its clinical application.and analyze the possible mechanism of action.provide the basis for further research of traditional Chinese medicine in treatment of functional dyspepsia.Methods:By using the method of random parallel controlled,will meet the functional dyspepsia patients with spleen deficiency and qi stagnation syndrome diagnostic criteria,were randomly divided into treatment group and control group.Treatment group was given Su medicine No.3,daily1agent,water decoction into300ml,morning and evening meals before each150ml;The control group was given Domperidone Tablets (domperidone).10mg each time,3times a day.half an hour before the oral,other treatments with other has a therapeutic effect on the disease of traditional Chinese medicine.western medicine or affect the test result shall not during the trial,4weeks for1courses.2courses were observed.Changes of two groups before and after treatment were evaluated the clinical symptoms,signs,before and after the treatment of water intake,satiety index threshold amount of drinking water,and the adverse reaction,patient compliance.All the data were statistically analyzed with SPSS17.0statistical software.Results:〥iagnosed and included functional dyspepsia of Spleen Deficiency and Qi Stagnation60patients (treatment group of30patients in the control group of30patients),the two groups before treatment,gender,baseline data for age,duration.Hp infection,etc.Statistically,the difference no obvious significance,comparable.②After treatment,the group total score syndromes comparison:two groups of patients,respectively,and the average points before treatment compared by t test,the difference was significant(P<0.01);comparison between the two groups,the treatment group than the control group by t test,the difference was significant(P<0.01).③After comparing the efficacy of traditional Chinese medicine treatment groups:the treatment group syndrome in6cases were markedly improved.effective21cases,invalid in3cases;The control group was2cases.effective18cases,invalid in10cases.The markedly effective and effective consolidated total efficiency,the treatment group was90.00%,66.67%in the control group,the chi square test.Z=4.812,P=0.029<0.05,with significant difference.④Comparison of two groups of single western medicine integral of symptoms after treatment:the treatment group patients with postprandial fullness discomfort,early satiety,epigastric pain,epigastric burning sensation and other symptoms improved better than the control group,by t test,P<0.05,the difference was statistically significant.⑤The two groups after treatment the total integral comparison of symptoms of Western medicine:the treatment group and the control group of Western medicine symptomatic integral average decreased,the rank sum test,P<0.01,significant difference.The comparison between two groups,group mean scores decreased significantly than the control group after treatment,the rank sum test,Z=-4.182,P<0.01,with significant difference.⑥The two groups after treatment of WLT:Two groups of patients with threshold amount of drinking water and enough amount of drinking water were significantly increased compared with before treatment,the t test,P<0.01,significant difference.The comparison between two groups,the t test,.P>0.05,without significant difference.⑦Liver and renal function tests were within normal range,the two groups had no adverse reaction.Conclusion:From the preliminary clinical research perspective,Su medicine No.3can obviously improve the spleen deficiency and qi stagnation of functional dyspepsia patients with syndrome of traditional Chinese medicine and Western medicine clinical symptoms,improve the threshold amount of drinking water and enough water quantity,the overall effect is better than domperidone,and safe,effective,and has wide application prospect,it is worth further study.