The Clinical Reseach On Relationship Between TCM Type Of Syndromes And Sex Hormones Before And After Menopause

Objective:Through a questionnaire survey of menopausal syndrome patients in general, clinical symptoms,observation of E2, FSH, LH and other hormones index,data analysis, to explore whether there is a correlation between TCM syndrome type and sex hormones; andsyndrome differentiation and treatment of patients, the clinical curative effect and the changes of sex hormoneswere observed before and after treatment, further to explore the relationship between type of syndrome and sex hormones, which demonstrated the objective basis forthe occurrence and development of this disease, TCMunderstanding internal relations and laboratory index, provides the objective basis for the syndrome differentiation and treatment of this disease, Chinese medicine dialectical diagnosis and treatment to establishnew model.Methods:A questionnaire, patients were face-to-face questionnaire, collecting general, Chinese medical information, menopausal syndrome (TCM rating scale),Menopause Rating Scale (MRS), aboratory examination,FSH E2, LH, data collection completed analysis and correlation with TCM syndrome differentiation; at the same time, before and after treatment in patients with clinicalsymptoms, sexual hormone level and comparative analysis was used to observe the changes of. Results:the clinical symptoms of patients age syndromesbefore and after menopause showed more46-50years old. From the course of disease seen in1years, the number of people. Patients with mild to moderate degree of common. Traditional Chinese medicine syndrome ofhyperactivity of fire due to yin deficiency, heart kidney is not handed in, two of kidney yin deficiency, deficiency ofkidney yang, kidney yin and Yang respectively accounted for31.37%,29.9%,19.61%,14.22%,4.9%. The level of E2decreased significantly in postmenopausal women in perimenopausal period, there was statistically significant(P<0.01) FSH levels were significantly higher in perimenopausal patients, there was statistically significant(P<0.01), LH level was high in perimenopausal period,but the difference was not statistically significant (P>0.05). Menopausal syndrome type of TCM syndromesdistribution and no difference in age, duration of disease,but are associated with menopausal status. Inperimenopausal period, patients with kidney yin deficiency, Yin Huo Wang, heart kidney incoordinationcommon, postmenopausal, common deficiency kidney yang deficiency, kidney yin and Yang two. According toMenopause Rating Scale (MRS) and mental symptom frequency, high to low:hot flashes sweating, sleep, Yi Jire, joint/muscle discomfort, heart discomfort, fatigue,anxiety, depression, bladder problems, problems, vaginal dryness. The analysis found between syndrome type of traditional Chinese medicine and psychosomatic symptoms distribution, hyperactivity of fire due to yin deficiency hot perspire the highest points, heart kidney incoordination problems with sleep, the highest points.The average level of hyperactivity of fire due to yin deficiency and heart kidney incoordination in patients with E2was significantly lower than other syndromes (P <0.05), while FSH, LH levels increased significantly than the other groups (P<0.05). The traditional Chinese medicinetreatment, clinical symptoms were followed up the patientswere significantly improved, TCM syndrome score lower,MRS integral is reduced, the difference was statistically significant (P<0.01); elevated E2levels after treatment,FSH level decreased, hyperactivity of fire due to yin deficiency group before and after treatment weresignificantly different (P<0.05), no significant others the difference between the groups (P>0.05).Conclusion:The period of clinical symptoms syndromesbefore and after menopause patients were mainlyconcentrated in the46～50age, in patients within1years of onset and clinical manifestations of patients, with mild to moderate. Hyperactivity of fire due to yin deficiency, heart kidney disharmony, kidney yin deficiency is the mostcommon syndrome type of syndromes before and after menopause. Combined with the traditional Chinese medicine syndromes in patients with clinical symptoms andthe distribution characteristics of before and after menopause, summarize the basic pathogenesis of thesyndrome of kidney yin deficiency, heart and liver partial wang. Menopausal women endocrine changes in total isincreased levels of E2, FSH and LH levels decreased,kidney essence deficiency and low estrogen relatedanions, FSH, LH changes into in vivo and is related to the degree of fire.