Autologous Stem Cells Transplantation In The Treatment Of Critical Limb Ischemia

High incidence of peripheral vascular disease is difficult to treat, withthe rise of aging, the incidence of peripheral vascular disease alsoincreasing, which gives clinicians a very big challenge, giving patients andsociety great burden; now the drug therapy, traditional surgery,endovascular therapy are the main ways; such treatments established in thecase of the unobstructed outflow tract, but the outflow tract occlusion andextensive vascular disease, above treatments are poor，traditional surgicaltreatment demanding conditions and great trauma caused, endovasculartherapy is a minimally invasive treatment, but high cost; when treatment inthe cart, burgeoning biological therapy offers new hope, less demandingcondition, good treatment effect, suitable for wide range severe peripheralvascular ischemia disease, provide new hope for patients.Biological treatment includes cell transplantation therapy, cytokine therapyand gene therapy, cell transplantation therapy is mainly, biological therapyis that lack of development of late, but late development，mechanismunclear, non-uniform standard assessment, adverse events unclear，areshortcomings.