Relationship Between Intracranial Pressure, Cerebral Perfusion Pressure, Computerized Tomography Scan Characteristics And Prognosis In Moderated And Severe Traumatic Brain Injury

Objective: To research the relationship among intracranial pressure,cerebral perfusion pressure with CT scan characteristics, and these therelationship with prognosis should be all included after moderated andsevere traumatic brain injury, for guiding the treatment decisions andassessing prognosis.Methods:42patients of moderate and severe traumatic brain injurywere admitted and the admission GCS score≤12. Patients all underwentintracranial pressure monitoring after clear diagnosed. Head CT wereexamined within24hours after injury. Recorded the values of intracranialpressure within24hours after injury, and the cerebral perfusion pressureswas calculated according to MAP（CPP=MAP-ICP）. The Rotterdam CTscores was calculated according to the CT scan characteristics, such as thestatus of basal cistern, shift, tSAH or IVH and mass lessiongs aftertraumatic brain injury. The Glasgow Outcome Scale score has been assessed within6months after injury. These factors were analyzedstatistically.Results:1.There are significant difference of ICP、CPP in individual CTscan characteristics(P<0.05).The ICP、CPP and Rotterdam CT score havesignificant difference in favourable and unfavourable group(P<0.05).2.The relationgship between Rotterdam CT score、the status of basalcistern、shift and ICP is: rho=0.703，rho=0.666，rho=0.482, and the CPP is:rho=0.863，rho=0.840，rho=0.578, the difference are significan（tP<0.05）。Conclusions: Both ICP、CPP and the Rotterdam CT score have goodvalue for assessing prognosis with patients who suffered morderated andsever traumatic brain injury; There are good relationship betweenRotterdam CT score and ICP、CPP, which can be used for guidingtreatment based on ICP monitoring.