The Clinical Observation On Acute Exacerbation Of Chronic Pulmonary Heart Disease (Phlegm And Blood Stasis Syndrome Differentiation) Treated With Huoxue Dingchuan Decoction

Objective：on the basis of Western treatment system, for acute exacerbation ofchronic pulmonary heart disease of phlegm and blood stasis syndrome differentiationin patients, with Qingfei phlegm, blood stasis and synergistic treatment efficacy ofDingchuan Decoction in western medicine, can quickly improve symptoms andtreatment of diseases of the objective, the collaborative treatment of acuteexacerbation of chronic pulmonary heart disease and provide scientific data supportfor traditional Chinese medicine and Western medicine.Methods:72cases of acute exacerbation of chronic pulmonary heart disease ofphlegm and blood stasis syndrome differentiation patients, randomly divided into thetreatment group (36cases) and control group (36cases), the control group was treatedwith oxygen therapy, anti infection, bronchodilator, diuretic and other conventionaltreatment of Western medicine, the treatment group in the conventional westernmedicine foundation treatment, oral Huoxue Dingchuan decoction. After the end oftreatment in the two groups were the symptom score, clinical symptoms, six minuteswalk test (6minutes walk test,6MWT), saturation of blood oxygen (saturation ofblood oxygen, SaO2), blood rheology, antimicrobial use time were collected andanalyzed, which were evaluated comprehensively and objectively in two groupscurative effect.Results:(1) basic information: the two groups of patients before treatment,gender, age, course of disease, the heart function classification, oxygen saturation,TCM symptoms integral,6minutes walking distance, blood rheology test results ofeight basic information, all the results were not statistically significant (P>0.05);(2)TCM symptoms: two groups of patients with dyspnea, phlegm, sputum character,edema, cyanosis, tongue, a treatment significantly improved (P <0.01), and the treatment group in the breathing difficulties, phlegm, sputum character, tongue fouraspects were better than the control group (curative effect P <0.05);(3) in symptomtotal score: two groups of patients after the treatment of TCM syndrome than beforetreatment were significantly improved (P <0.01), and the treatment group improvedbetter than the control group (P <0.05);(4) disease curative effect: in the total score,treatment group total efficiency and markedly effective rate were97.1%and40%, thecontrol group were90.6%and18.75%, the control group and the treatment groupcurative effect is better than that of (P <0.05);(5)6MWT: two groups of patientsafter6minutes walking distance significantly increased compared with beforetreatment (P <0.01), the treatment group to improve the situation In the control group(P <0.05); in the6MWT effect, the total effective rate of treatment group was94.3%,control group, the total effective rate was71.9%, the curative effect of treatmentgroup was better than that of the control group (P <0.05);(6) saturation of bloodoxygen: two groups of patients after SaO2treatment significantly improved aftertreatment (P <0.01), the treatment group was better than the control group (P <0.01);(7) determination of blood rheology: whole blood viscosity, whole blood low shearviscosity of two groups after treatment, plasma viscosity, erythrocyte sedimentationrate, hematocrit, erythrocyte aggregation index were significantly decreased comparedwith those before treatment (P <0.01), the viscosity of whole blood viscosity, wholeblood in low, plasma viscosity, hematocrit, erythrocyte aggregation index five,treatment group than in the control group decreased more obviously (P <0.05); thetwo group patients after ESR had no difference (P>0.05);(8) the use of antibacterialdrugs: treatment group at antimicrobial drug use time was significantly shorter thanthat of control group (P <0.05).Conclusion: through72cases of acute exacerbation of chronic pulmonary heartdisease (phlegm and blood stasis syndrome differentiation) the clinical curative effectobservation and analysis for14days for patients, a preliminary validation of thecombined treatment of the disease with traditional Chinese and Western medicine,western medicine therapy is better than pure. The results of this study showed that, thetreatment group was treated with the acute exacerbation of chronic pulmonary heartdisease (phlegm and blood stasis syndrome differentiation) can improve thesymptoms of patients, increase the6MWT distance, improve the oxygen content ofarterial blood, improve the hemorheological index, shorten the time of using antibiotic, faster control disease, improve the quality of life of patients, provide objective basisfor treatment of this disease with combination of TCM and Western medicine.