The Effects To PSG And5-HT Of Heart-spleen Deficiency Insomnia Patients By Three Parts Tuina-therapy

Objective:This study adopts the method of clinical own control,By observing thechanges before and after treatment in patients of three parts tuina-therapy withheart-spleen deficiency type of insomnia PSG structure and5-ht,To explore the effectmechanism of sleep structure in patients with heart-spleen deficiency type of insomniafrom molecular biology.To elevate the treatment results,better theory basis for tuinain the treatment of improved.Methods:According to the research method of self-control before and aftertreatment,The30patients with heart-spleen deficiency type of insomnia met theinclusion criteria.put to use the three parts tuina-therapy,Treatment for15days as acourse of treatment,once a day.Through the monitoring of polysomnogram before andafter treatment, observe the total sleep in patients with insomnia and deep sleep time,sleep latency, number of awakening and non rapid eye movement sleep time of eachstage,To analyze the changes of the sleep structure.The level of plasma5-HT weremeasured before and after the early morning of serotonin in patients with insomniatreated with mechanism analysis of sleep improvement.Results:12cases got cured,13cases marked effectiveness,3cases effectiveness,and2cases failure,the total effective rate was90%.2groups of inner self comparison:5-serotonin levels before and after treatment in patients with insomnia have significantdifference (P <0.05), showed thatthree parts tuina-therapy can significantly improvethe5-serotonin levels in patients with insomnia.3through the monitoring ofpolysomnogram before and after the treatment with the process of sleep, total sleep time, sleep latency and the number of awakening were significantly different (P <0.05),Show the three parts tuina-therapy, can effectively improve sleep process inpatients with insomnia, can increase the total sleep time, shorten the sleep latency,reduce the number of awakening.4N1and N3in the NREM sleep and REM sleep hadsignificant difference for the before ang after treatment(P <0.05).Show that the thethree parts tuina-therapy can increase deep sleep stage N3,REM sleep,reduce theshallow sleep N1sleep,no significant improvement in the N2phase of sleep.Conclusion:1the three parts tuina-therapy to improve the5-HT level in patients withinsomnia2the three parts tuina-therapy effectively adjust the sleep structure inpatients with heart-spleen deficiency type of insomnia, the total sleep time and REMsleep and non REM sleep deep sleep time increased, reducing the number ofawakening, improve sleep quality.3.considered the mechanism of the three partstuina-therapy treatment of insomnia of heart-spleen deficiency type,its regulation inpatients with5-serotonin levels and improve the sleep structure and relieve insomniasymptoms.