Clinical Observation Of Dampness Huoxuetongluo Treatment Of Acute Gouty Arthritis

PurposeIn this study, by observing the heat and dampness, Huoxuetongluo law and evaluation of the efficacy of acute gouty arthritis its safety, investigate heat and dampness, Huoxuetongluo method for acute gouty arthritis mechanisms and prognosis for the treatment of acute gouty arthritis provide a reasonable solution for the treatment of acute gouty arthritis medicine to find new ways.Method60patients with acute gouty arthritis patients met the inclusion criteria, a prospective randomized controlled way into control group and treatment group,30cases in each. Take a different treatment groups, the treatment group:1, heat and dampness, soups Huoxuetongluo(2pieces of cork pieces pack a bag herb Smilax2pieces pack2pieces castor seed packets1packet triangular pieces of cow teeth vigorously Yiyiren2pack2pack pieces pieces pieces per package Flemingia two pieces of earthworm Hu a pack a bag of red stars Shao a licorice pieces pack a bag. taking400ML boiled water, morning and evening empty stomach, warm clothes) Patients with lower extremity pain evident, plus pieces hyssop2packs, pieces centipede2packages; obvious pain in the upper limbs, plus pieces Guizhi package, a package Angelica teeth, teeth TPG1package; wet weight in the heat, add pieces Plantago a package; TGA wet, add pieces of honeysuckle a package;2, celecoxib (pfizer pharmaceuticals),200mg, twice daily; treatment for seven days. Control group:1, with1.0mg of oral colchicine for the first time, every2to3hours after oral administration of0.5mg, until the joint pain relief, but the first day the maximum amount can not exceed5mg; until the emergence of three one of withdrawal MEASURES:①pain, inflammation were relieved;②nausea, vomiting, diarrhea, etc.;③total24hours of6mg; colchicine medication regimen is not more than two days;2, celecoxib (pfizer pharmaceuticals),200mg, twice daily. Medication treatment for seven days. Before treatment and1week after treatment were observed in patients with joint swelling index, uric acid, erythrocyte sedimentation rate, ultra-sensitivity C-reactive protein; monitor liver function, renal function, fill in the table of adverse reactions observed clinical efficacy and safety evaluation of the two groups, comparing the two whether the statistically significant groups.Result1, two groups of patients participating in trials without gender, disease duration, age, joint pain, affected joints, joint function and other aspects of significant difference (P>0.05), comparable; in terms of TCM symptom score changes after treatment after reducing the mean symptom score were significantly different (P<0.05), improvement in joint syndromes medicine is better than western medicine.2, one week after treatment, the treatment group recovered25cases were cured,2cases,2cases,1case, the total efficiency of96.67%in the control group cured18cases,2cases markedly effective in5cases, five cases, the total efficiency of83.33%, compared two groups P<0.05, significant difference.3, the joint main symptoms indicators:1week after treatment, both groups are effective mitigation, there is a significant difference (P<0.05) compared with pre-treatment of joint pain, swelling, skin temperature, features, etc., showed no significant difference between the two groups (P>0.05). Help groups have a role in improving the symptoms of joint pain.4OUTCOME MEASURES:1week of treatment, serum uric acid, erythrocyte sedimentation rate, ultra-sensitive C-reactive protein were lower, there were significant differences (P before treatment<0.05), no significant difference (P between groups>0.05). Help groups can lower blood uric acid and inflammatory markers.5, will be relatively safe:the course of treatment, the treatment group had abdominal pain and diarrhea in2patients in the control group had abdominal pain, diarrhea and other gastrointestinal symptoms in5cases,3cases of allergic skin rashes, two adverse reactions were6.67%and26.67%, data showed a statistically significant difference (P<0.05).ConclusionAfter treatment, patients were joint pain, limited mobility have improved, uric acid, erythrocyte sedimentation rate, ultra-sensitive C-reactive protein were lower, but in pain control, eliminating inflammation, the treatment group than the control group, compared with western medicine combined with western medicine alone, significantly reducing the adverse reactions, play to the advantages of TCM treatment facilities, and a significant reduction in adverse reactions.