Evaluating The Efficiency Of Partitioned Moxibustion In Treating Bone Marrow Inhibition Caused By Chemotherapy

ObjectiveTo evaluate clinical effect via treatment of Ginger moxibustion and monkshood cake moxibustion for bone marrow inhibition as the result of chemotherapy for malignant tumor.MethodFirst, withdraw the patient bone marrow after the chemotherapy of malignant tumors to suppress the patients56cases, then divide it into two groups:group of Ginger moxibustion select prone-positioned acupoints (Dazhui, Pishu, Weishu, and Shenshu) and select supine-positioned acupoints (Zhongwan, Qihai, Guanyuan, and Zhusanli), alternatively moxibustion the above points at every next day; the moxibustion method of monkshood cake moxibustion group is the same with the Ginger moxibustion group.Both groups were treated for14days to observe the condition of marrow suppressed-before treatment,7th day treatment,14th day treatment and2weeks after treatment respectively. Apply the changes of peripheral counts in white blood cell count as the main observation guideline, in the mean time, observe the main improvement scored on clinical TCM symptoms and KPS (before and after treatment) of the two groups of patients.ResultsStatistic accessed that there is no significant difference (P>0.05) amongst Ginger moxibustion group and monkshood cake moxibustion group patients including gender, age, WBC, HGB, PLT, main symptom scored of TCM, KPS functional scores,etc. however, they are comparable.After14days of treatment, Ginger moxibustion group markedly at18cases, validity at7cases, invalidity at3cases, gross effective rate at89.3%; monkshood cake moxibustion group marked17cases, validity at9cases, invalidity at2cases, gross effective rate at92.9%. After statistic assessment, it shown that both groups are not valid for statistic (P>0.05).Peripheral blood cells:①WBC:On the7th day of treatment, both was statistically significant in the count of the two groups of peripheral WBC in compared with before treatment (P<0.05); on the14th day of treatment, the count of peripheral WBC for two groups of patient continue to increased, difference in comparison with7th day treatment was also statistically significant (P<0.05), Two weeks after14days of continuous treatment, the count of peripheral WBC declined for both groups of patients, but the difference compared with the14th day treatment was not statistically significant (P>0.05), further it had no significant difference between the four time points (P>0.05) among the two groups.②PLT:Difference compared between the two groups was not statistically significant (P>0.05), further the comparison of the14th day treatment and before treatment of the two groups of patients were not statistically significant (P>0.05), it only exhibit significant difference in two weeks after treatment, before treatment and14th day treatment (P<0.05).③HGB:The difference compared analyzed among the14th day treatment and two weeks after treatment was not statistically significant.TCM main symptoms:The comparison difference in TCM symptoms scoring amongst before treatment,14th day treatment and two weeks after treatment was not statistically significant for the two groups of patient (P>0.05). But each group were decreased significantly in the14th day, it was significant when compared to before treatment (P<0.05), rebounded after two weeks of treatment and it is statistically significant when compared with the14th day treatment (P<0.05), but still lower than before treatment, the difference was statistically significant (P<0.05).Quality of life:During the treatment process, both QQL scores were improved for the two groups of patients, the comparison of the14th day treatment and before treatment was significant (P<0.05), but declined after the end of treatment; the comparison among14th day treatment and before treatment both was statistically (P<0.05). The comparison of the three time points among two groups has no significant difference (P>0.05). KPS function score changes in proportionate to QOL scores.Conclusion①Ginger moxibustion and monkshood cake moxibustion both can be effective in promoting peripheral counts of WBC after chemotherapy for bone marrow inhibition patients, effecting time and maintain time of two groups is similar;②Both treatments can improve the general physical condition and clinical TCM symptoms by reducing toxic side effects and improving the living quality of patients;③Integrated effect is considerable for the two treatment method.