| Background and Objective：Nowadays,as the speeding up of living tempo,the enhancing of people’s living standardand the aging of population, Coronary heart disease(CHD) growing seriously threat to humanlife and health due to the progress of the disease and the high rate of sudden death. It is themost important thing to give a correct diagnosis to coronary heart disease in time,that willimprove the prognosis of the patients disease,control the disease progression and improve thequality of the patients’ life.This article aims to observe the relationaship of the changes of theECG and the lesions of the coronary angiography(CAG) of the patients with coronary arterydisease.Studying retrospectively to search the appearing of fQRS wave in the inferior leadsand comparative analyzing the relationship of coronary artery lesions with its range, severityand vessels involved.To explore the Clinical significance of fQRS wave in the leads inferiorwith coronary artery lesions.and provide a new reference index for the clinical diagnosis ofcoronary heart disease.Methods：A total of442cases were selected in this retrospective study. The patients who werehospitalized in cardiology department of Liaoning People’s Hospital from Oct2012to Sep2013. All of the chosen cases should had no myocardial infarction.294cases were male,148cases were female,aged39to87years, the mean age was(57.9±18.3).Each research object’s12-lead ECG and CAG were carefully obsevered such as the emergence of fQRS wave,theposition of fQRS wave in the leads of12-ECG and the corresponding results of coronary angiography, including coronary artery lesions with its range, stenosis level and vesselsinvolved.Organize the data as follows.(1).Based on the presence or absence of fQRS in ECGdivide into two groups:a fQRS wave group(n=275)and a non-fQRS wave group(n=167);(2)Based on the presence or absence of fQRS wave in inferior leads divide into twogroups:a fQRS wave in inferior leads group(n=206)and a non-fQRS wave in inferior leadsgroup (n=236);(3).Based on the range of coronary artery lesions into threegroups:triple-vessel disease(n=215),double-vessel disease(n=133),single-vessel disease(n=94);(4).Based on the involved vessels in coronary artery lesions divide into two groups：the rightcoronary artery disease group(n=305),non-right coronary artery disease group(n=177);(5).Based on the most important coronary artery diameter stenosis level were divided intothree groups:I.90%≤D≤100%very severe stenosis group (included chronic total occlusion21cases) of218cases(for49.3%); II.70%≤D <90%severe stenosis group of165cases,accounting (for37.3%); III.50%≤D <70%mild stenosis group of59cases(foe13.3%).Results：(1)Significant difference in fQRS wave detection rate was observed among patients withlesions in different counts of vessels（p<0.05），to be specific,triple-vessel disease detectionrate (71.2%)was higher than double-vessel disease and single-vessel disease(57.1%and48.9%respectively),among them,the difference with single-vessel disease wassignificantly(p<0.01）;the different detection rate among double-vessel disease andsingle-vessel disease were no significant(p>0.05）。(2)Significant difference in fQRS wave detection rate was observed between differentleads in ECG, among them, the detection rate in inferior leads（46.6%）was significantlyhigher than that in anterior leads and lateral leads(all p<0.01）;the different detection rateamong in anterior leads and lateral leads (16.3%and18.3%respectively)were nosignificant(p>0.05).(3)The detection rate of fQRS wave of inferior leads in multivessel disease（52.0%）washigher than Single-vessel disease（26.6%）,the difference is significantly（p<0.01）.(4)No significant difference in fQRS wave of inferior leads detection rate was observedamong the right coronary artery disease group and non-right coronary artery disease group（p>0.05）. (5)No significant difference in fQRS wave of inferior leads among different lesionstenosis level（p>0.05）.Conclusion：The fQRS has some clinical significance in apart of coronary heart disease. It can be anoninvasive criteria in a certain degree to estimate coronary heart disease. In this study we getthe following opinion:(1)The fQRS wave in inferior leads can be used as a predictor of therange of coronary artery lesions.(2)Patients with coronary artery disease，the detection rate ininferior leads is higher than that in anterior leads and lateral leads.(3)The fQRS wave ininferior leads can be used as a predictor of coronary artery multivessel lesions. |
