Study On Eye Movement And Cognitive Function Of First-episode Schizophrenia

Objective:Comparing first-Episode schizophrenia patients and normal controlgroup in exploratory eye movement and differences in cognitive function, to findcorrelation between exploratory eye movement and cognitive function, and to explorejoint detection exploratory eye movement and cognitive functioning in schizophreniacan improve early diagnosis accuracy.Methods: DEM-2000eye movement detection equipment, continuousperformanee test-identical pairtest Hopkins Vocabulary learning Test-Revision andthe verbal fluency test in60patients with schizophrenia (patient group) and normalhealthy people (control group) test the cognitive function and detected.: DEM-2000by measuring eye movements of two populations ofexploratory eye movement gazepoints and reactive inquiry points were detected; withcontinuous performanee test-identical pairtest, Hopkins Vocabulary learning Test-Revision, the verbal fluencytest on two cognitive function tests.Results:1、exploratory eye movementpatient group exploratory eye movement in NEF (21.60±6.569) wassignificantly lower compared with the control group, RSS (4.83±1.950) lower thanthe normal control group (30.67±7.097,7.58±2.580), the differences werestatistically significance (p <0.01).2、cognitive function（1）continuous performanee test-identical pairtest in the two-digit group ofpatients, three-digit, four-digit sensory discrimination d values were lower than thenormal control group, the average sensory discrimination d values (2.063±1.007)was significantly lower than the control group (2.865±0.960), the difference wasstatistically significant (p <0.01).In the missing number (12.58±7.06) lower than the control group (3.73±3.837)in patients with continuous performanee test-identical pairtest group, the differencewas statistically significant; mistaken number (2.16±2.75) than the control group (1.56±1.897), but not statistically significant; average response time (620.6578±1.1058) was significantly higher than the control group (489.2532±81.7225), thedifference was statistically significant at the0.01.（2）Patient group Hopkins Vocabulary learning Test-Revision total number ofcorrect lower than the control group, statistically significant differences.（3）the verbal fluency test in patients less than the total number of correctnormal control group, the difference was statistically significant (p <0.01).3、exploratory eye movement and relevance of cognitive functionPatients exploratory eye was in motion NEF total sensory discrimination d valueof a positive correlation (r=0.918); positively correlated with Hopkins Vocabularylearning Test-Revision total number of correct showed a correlation coefficient of0.857; and the verbal fluency test were positively correlated (r=0.820); and Culturethe degree of positive correlation.Patients exploratory eye movement RSS and NEF,the total number of correct Hopkins Vocabulary learning Test-Revision, and the totalnumber of the verbal fluency test little relevance, not statistically significant; sensorydiscrimination, but the average value of d continuous performanee test-identicalpairtest was positively correlated coefficient of0.305.Conclusions:1, patients with schizophrenia exploratory eye movement (NEF,RSS) abnormal and defective cognitive function, such as a serious lack of sustainedattention, verbal memory decreased verbal fluency obstacles.2, there is a exploratory eye movement significant correlation with cognitivefunction.3, exploratory eye movement joint tests of cognitive function can improve theaccuracy of the early diagnosis of schizophrenia.