Analysis On Body Composition And Research On Related Factors In Maintenance Hemodialysis Patients

Objective:To measure body composition and Overhydration in maintenancehemodialysis patients with body composition monitor(BCM). To compare the relationbetween body composition and Blood biochemical parameters and to assess theOverhydration, to provide a scientific basis on assessing the nutritional status and thedry weight for clinical.Method：We select57MHD patients and measure their body composition with BCMand collect their blood samples before each dialysis.we detected their serumcholesterol,serum triglyceride,serum albumin,serum hemoglobin, and serumcreatinine, etc. Then divided into2groups according the mean value of BMI、fattissue of unit surface area and muscle tissue of unit surface area, then compare theblood biochemical parameters between the2groups and do a correlation analysisthem. To take the difference value between OH measured with BCM and the actualclinical ultrafiltration volume into groups. Of which group A are the difference valueexceeding300ml, and group B are less than or equal to300ml.Respectively,werecorded the numbers of occurrence of adverse reactions occurred in dialysis, then wedid a Chi-square test between the two group.Result:1. Compared the BMI high group （BMI≥21.68kg/m2）and BMI low group（BMI<21.68kg/m2）, the former’s fat tissue of unit body surface area is higher thanthe latter’s (p=0.000）, the result of single factor correlation analysis is a positivecorrelation between BMI and fat tissue unit surface area (r=0.588, P=0.000). Themuscle tissue of unit surface area showed no statistically significant differencebetween the two groups (（p=0.376>0.05), there is no correlation between BMI andmuscle tissue of unit surface area(r=-0.109；P=0.419).2. Compared with group of high fat tissue of unit surface area （≥12.29kg/m2）andthat of low fat issue of unit surface area（<12.29kg/m2）, the former’s cholesterol, triglyceride, hemoglobin is higher than latter’s（p=0.006,0.047,0.000）. there is apositive correlation between the fat tissue of unit surface area and cholesterol,triglyceride, hemoglobin (r=0.370，0.403，0.405；p=0.010，0.005，0.002).3. Compared with group of high muscle tissue of unit surface area （≥22.80kg/m2）and that of low muscle tissue of unit surface are（<22.80kg/m2）, the former’s serumcreatinine and serum albumin is higher than the later group,(p=0.015,0.033). there is apositive correlation between muscle tissue of unit surface and serum creatinine,serumalbumin (r=0.416，0.315；p=0.001，0.018).4. We recorded the incidence of adverse reactions about hypotension, nausea andvomiting, and convulsion, etc. between the two groups in dialysis,chi-squared testabout the adverse reactions showed there is statistically significant difference(X2=7.402，P=0.007). When the difference value between OH measured with BCMand actual ultrafiltration volume exceeds300ml, the adverse reaction occurrence rateis apparently higher than that in group with difference value less than or equal to300ml. It shows that OH measured with BCM is basically identical with patients’actual OH, namely, the measured dry weight is simply identical with patients’ actualdry weight.Conclusion: In MHD patients,1.OH measured by BCM can assess patients’ dryweight conveniently、accurately and objectively。2.Application of BCM was accurate,non-invasive and quick and it has importantclinical value for assessment of the nutrional status of MHD patients.