The Relationship Between Hypersensitive C-reactive Protein And Anemia In Patients With Diabetic Nephropathy Hemodialysis

Objective:1.This study aims at measuring high-sensitivity C-reactive protein(hs-CRP) levels, to explore the level of hs-CRP changes of diabetic nephropathy inpatients with non-diabetic nephropathy in maintenance hemodialysis patients.2.Discuss the differences of severity of anemia and the situation ofmicro-inflammatory state of diabetic nephropathy in patients with non-diabeticnephropathy. By correlation analysis with the average level of hs-CRP and anemiarelated indicators, to further clarify the relationship between micro-inflammatory stateand anemia, in order to forecast the severity of anemia in patients with diabeticnephropathy for providing a further assistance.Materials and methods: To select patients with hemodialysis treatment ofQinghai People’s Hospital from December2011to December2013.In them, primarydisease of diabetic nephropathy is30cases, and non-diabetic nephropathy is30cases.Their hemodialysis time between3to18months. The control group: healthy personsin Qinghai People’s Hospital Medical Center are30cases. Record basic informationabout these patients.Collect observed objects before dialysis which of fasting glucose,albumin, hemoglobin, hematocrit, serum iron, high-sensitivity C-reactive proteinand other relevant indicators in the Dialysis day. The data are used SPSS17.0software for statistical analysis.Results:1.Hs-CRP average levels in patients with diabetic nephropathy andnon-diabetic nephropathy are higher than the control group, and Hb、Hct levels are onaverage lower in which two groups than the control group. The average level ofhs-CRP in patients with diabetic nephropathy is higher than non-diabetic nephropathygroup;Patients with diabetic nephropathy whose Hb、Hct average levels are lowerthan the non-diabetic nephropathy group.2.Hs-CRP in diabetic nephropathy patientswith Hb and Hct are negatively correlated.Conclusions:1. Maintenance hemodialysis patients exist micro-inflammatorystates; patients with diabetic nephropathy micro-inflammation are higher than non-diabetic nephropathy.2.Anemia severity in patients with diabetic nephropathyserious than the non-diabetic nephropathy.3.Hs-CRP and Hb、Hct average levels inpatients with diabetic nephropathy are inversely proportional, suggest thatmicro-inflammation is closely associated with the severity of renal anemia, on acombination of previous conclusion diabetic nephropathy patients have highermicro-inflammation level. So micro-inflammatory state may be an important riskfactor for the occurrence of severity anemia in patients with diabetic nephropathy,hs-CRP may provide another reference for predicting the severity of anemia.