The Comparative Study Of Chronic Renal Failure Patients Between Sustained Low-efficiency Daily Dialysis (SLEDD) And Intermittent Hemodialysis (IHD)

Objective: To compare the different efficacies of chronic renal failure(CRF)patients between sustained low-efficiency daily dialysis（SLEDD）and intermittenthemodialysis（IHD), study the characteristics of these two kinds of dialysis patterns,in order to provide the basis for different clinical patients choosing a scientific andrational hemodialysis therapy.Materials and methods: During the time from November2012to March2013,there were40CRF patients who needed hemodialysis therapy from Qinghai provincepeople’s hospital gathered in this study. Divided them into group SLEDD and groupIHD,20patients in each group,they were treated by SLEDD or IHD.Recorded theirpersonal informations, monitored their blood pressure, blood solute clearancesituation and electrolyte changes before and after dialysis.Results:Two groups’ post-dialysis mean blood urea nitrogen(BUN), serumcreatinine(Cr), potassium(K+), sodium(Na+), calcium(Ca2+) and phosphorus(P3+), aswell as their mean arterial pressure(MAP) and their mean heart rate(HR) hadstatistically significant differences when compared with pre-dialysis(P<0.05).SLEDD group had a better effect than IHD group at Kt/V, potassium removeindex, sodium remove index,calcium remove index and phosphorus removeindex,these results were actually statistically significant (P <0.05), blood ureanitrogen rate of decline and creatinine remove index had no significant differences (P>0.05). The mean arterial pressure(MAP) of patients from two groups had fallen afterdialysis,but SLEDD group’s changing was smaller than IHD group,the difference wasin fact statistically significant(P<0.01).After dialysis,two group patients’ heartrate(HR) had slowed,but SLEDD group’s changing was less,the difference was reallystatistically significant(P<0.05).Conclusions: Sustained low-efficiency daily dialysis（SLEDD）and intermittenthemodialysis（IHD) can effectively remove the blood small solutes of patients withchronic renal failure,effectively reduce the mean arterial pressure, and heartrate.SLEDD was more effective than IHD to lower patients’ blood potassium, sodiumand phosphorus,elevated their blood calcium,had higher dialysis adequacy and a morestable hemodynamics.