Burdock Root Effective Parts Of The Preparation And Purge Role Of Experiments

Objective:Preparation burdock root six effective parts; and through the pharmacological experiments confirm burdock root screening and crude aperient effective parts.Methods:Burdock root of on pharmacognosy; Solvent, extraction, adsorption, etc according to the polarity of burdock root size extraction,, we prepared burdock water extractings group, burdock alcohol water extractings group, burdock ethanol-extraction content group, burdock80%ethanol to wash down parts, burdock chloroform extractings group, burdock petroleum ether extractings group and calculation yield; The method of small intestine motor with carbon push at the end of the pharmacological experimental method, and the specific design for:mouse randomly divided into7respectively group to physiological saline as control group, burdock root alcohol extract, burdock root water extract, burdock root extract, burdock root alcohol water petroleum ether extract, burdock root chloroform extraction, burdock root80%ethanol to wash down parts of the experimental group, the daily fill the stomach respectively to medicine, the continuous give7d, measurement of mice and time, first row black6h feces number and push rate, using SPSS13.0software to analyze, to P<0.05said with a statistical significance.Results:Using the method of burdock root senses are identified and determined that the compositae plants burdock (Arctium Lappa L.) the root; Burdock root each part yield respectively is:water extractings35.3%, ethanol-extraction, alcohol content38.3%water mix extractings from63.3%to0.67%, and petroleum ether, chloroform part part0.77%,80%ethanol to wash down parts7.3%; Pharmacological experiments show that burdock root water extraction group (the first row of black and time70.80min,6h excrement, promoting rate of51.8of56.80%, the same below), alcohol extract group (83.56min,42.5),46.51%) and the water extract of alcohol group (81.13min,44.8),48.13%) are higher than the blank group (100.99min,40.6),39.99%), of which the most significant water extract group (P<0.05), a statistical significance.Conclusion:Burdock root water extraction objects in the500mg/kg doses, filling the stomach to mice have obvious purge role.