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Evaluation Of Disinfectant Efficacy Of The OSG Weak Acid Disinfection

Posted on:2016-07-07Degree:MasterType:Thesis
Country:ChinaCandidate:J LiuFull Text:PDF
GTID:2283330482974209Subject:Prevention of Veterinary Medicine
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In the process of animal infectious diseases prevention and control, the use of disinfectants is an important way to eliminate pathogenic microorganisms, disinfectant disinfection efficiency is an important symbol of evaluate disinfectant effect. This study Japan OSG weak acid disinfectant development of the new company as the research object, according to the inspection standard for disinfection of the new type of disinfectant system ntevaluation, evaluate the sterilization effect of kill virus, metal corrosion, animal toxicity experiments and so on, to make sure it can be applied in captive pandas endangered animals and related captive wild animals with animal disinfection. The results of the study are as follows:l.OSG weak acid disinfectant kills bacteria and fungi bactericidal effect conforms to the basic requirementsAccording to the inspection technology standard for disinfection method and provided according to actual use of disinfectants, selects the carrier quantitative germicidal test method to test and determine the OSG weak acid disinfectant on escherichia coli, staphylococcus aureus, white staphylococcus, pseudomonas aeruginosa, brevibacterium black variant coli and Candida albicans kill for numerical respectively for 6,5,6,6,6, and 5, the results show that the OSG weak acid disinfectant of killing bacteria and fungi to numerical values were greater than 3, OSG weak acid disinfectant bactericidal effect conforms to the basic requirements.2.Organic matter of OSG weak acid disinfectant bactericidal action of basic no effectFor the study of OSG weak acid disinfectant in the presence of organic matter, the effects of the organic matter of disinfectant in this experiment with bovine serum albumin concentrations were 1%,0.1%,0.01% and 0.1% respectively. The test results showed that the concentration of the bovine serum albumin at less than 0.01%, OSG bactericidal effect of weak acid disinfectant had no effect on basic.3.Skin irritation test and vaginal mucosa stimulation test confirmed OSG weak acid disinfectant non-toxic roleChoose this experiment with rats as experimental animals, with skin irritation and vaginal mucosa stimulation method of evaluation of OSG weak acid disinfectant toxicity stimulation experiments. After skin irritation, through the observation to evaluate whether skin appears erythema and edema, etc; After vaginal mucosa stimulation, through evaluate the epithelial tissue presence of leukocyte infiltration of inflammation. The results showed that the skin irritation index is 0.25, according to the judgment standard judged without excitant; Vaginal mucosa stimulation index was 0.7, according to the judgment standard for without excitant; Histopathological examination showed that the OSG weak acid disinfectant and vaginal stimulation to the skin without obvious inflammation.4.0SG weak acid disinfectant weakly acidic disinfectants for inactivation of giant panda rotavirus testTo the giant panda rotavirus and MA 104 cells as the experimental material, through the determination of OSG weak acid disinfectant for giant panda rotavirus TCID50 change value to evaluate the disinfectant inactivated effect of giant panda rotavirus, and by 84 disinfectant rotavirus inactivated effect for the giant panda is the the disinfectant effect can be evaluated. Results show that the OSG weak acid disinfectant for giant panda rotavirus inactivated for numerical> 6,84 disinfectant for giant panda rotavirus inactivated for numerical> 4; Organic matter in bovine serum albumin experiments show that the influence of organic matter in less than 0.1% of the cases, OSG disinfectant can play a role of effectively kill the virus.5 Metal corrosive OSG weak acid disinfectant tests showed that the corrosion of different metals have different role, OSG can be used in the disinfection of beast of the fieldSelects the common material of carbon steel, copper, aluminum and stainless steel as experiment material, OSG disinfectant of corrosive experiment was carried out. The test results show that the corrosion of carbon steel, copper, aluminum and stainless steel ratio were 0.4418,0.0036,0.0067,0.0368; According to the material standard of judgment concluded that moderate corrosion strength of corrosion of carbon steel, copper corrosion strength as the basic non-corrosive, aluminum corrosion strength for mild corrosion, the corrosion of stainless steel for corrosion of mild intensity.Field disinfection test,17-24℃ at room temperature, relative humidity 40%-75%, under the condition of two kinds of test site in 100 ppm disinfectant disinfection treatment, disinfection effect time 30 min, the airborne bacteria elimination rate is more than 90% on average.
Keywords/Search Tags:OSG weakly acidic disinfectants, carrier sterilization, toxicity test, Inactivated viruses, corrosive, Field disinfection test
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