| As the aging population increases, the incidence of geriatric diseases, such as hypertension, diabetes, rheumatism etc. increases year by year. Because of these common diseases caused kidney disease also present a growth trend,as a commonly used medical devices for the treatment of kidney disease—Extracorporeal blood circulation therapeutic apparatus, Its stability and safety performance is a key factor, decided the majority of patients treated with blood purification means. Instrument Automation and biomaterials research changing, extracorporeal circulation therapeutic towards stability, security, human and physical care direction.This paper introduces the basic classification and research progress of disciplines of blood purification. This paper expounds the principle and application of various purification treatment model. For blood purification equipment research progress and deficiency, major improvements are put forward.According to the function of the equipment, and the division of modules, introduced the design idea and process of hardware and software in this paper.Introduces the design of driven part of stepper motor based on Subdivision technology. large number of sensors used in the text. Introduces data acquisition module Hardware module, it’s main conversion chip is AD7799 make anti-jamming design. STM32 using SPI control, program Download interface.Air bubble detection part according to the application requirements of this article. Designed bubble sensor and solenoid valve combination unit, to prevent air bubbles entering human body. Data processing part use AD7799 acquisition module. The blood temperature control scheme is proposed based on recent years a popular concept of "physiological dialysis". According to use higher temperature dialysate than human, the body temperature of the blood will be increased after purification. Design according to whether patients with a history of low blood pressure, setting a reasonable heating temperature of the heated portion of hemodialysis, reduce the incidence of hypotension complications.Design 485 anti-interference ability of multipoint communication module, Using Modbus -RTU communication protocol model, command parsing, according to the upper machine control power parts and monitoring module. Realization operations of hardware modules monitor and read and write, improve the reliability of communication. The entire hardware module uses u C/ 0S -II system for scheduling tasks, Make every task can real-time and orderly operation. Individual modules are controlled using the STM32, AD data acquisition using SPI communication control. The data collected using median filtering and moving average filtering processing. Improve the anti-interference ability of the AD and the safety and reliability of the system.Sub-module system experimental results show that, Data stability is good, can apply to the use of extracorporeal blood circulation therapeutic requirements. General AD converter, Pc control master hardware by 485 bus module. To ensure that in the event of a failure to cut off the hazards at fastest speed. Temperature control can reduce complications caused due to blood purification. Improve the safety performance of blood purification equipment and treatment process of human nature, maintain the life safety of patients. |