Composition And Process Crafts And Quality Standards Of Fufang Chuanbeijing Pian

In this study, single factor experiment, study explores the impact of compound materials ratio vabres Fritillaria fine films prepared, and the establishment of the compound by HPLC-ELSD detection vabres Fritillaria fine film Imperialine content approach.Ingredients ratio: the right amount of ephedra extract(ephedrine hydrochloride equivalent to 4.2g), vabres Fritillaria 50 g, tangerine peel 188 g, bellflower 188 g, Schisandra106 g, licorice extract 30 g, France Pinellia 150 g, 106 g polygala.Accessories: starch do fillers, binders do sucrose, talc, magnesium stearate as a lubricant. Citrus used per 1g 2.8g sucrose, 0.6g starch, magnesium stearate 0.019 g, talc 0.3g.Finished compound vabres Fritillaria fine films finished color brownish yellow or brown, bitter, slightly acrid taste, slightly sweet, licorice aroma. Tablet weight variation test and disintegration tests are in line with the "Chinese Pharmacopoeia" 2010 version of the tablet with the relevant provisions.Established by HPLC-ELSD and the internal standard method to detect compound vabres Fritillaria fine film Imperialine β nitrogen oxide method, chromatographic conditions: Column: C18 reverse phase column packing Alltima TM, particle size 5μm, 250 mm × 4.6mm; column temperature: 30C; mobile phase: acetonitrile: water: diethylamine = 65: 35: 0 3, the flow rate of 1 ml / min; detector: evaporative light scattering detector(Evaporative Light-Scattering Detector, ELSD); ELSD gasification temperature: 40 ℃; carrier gas pressure: 1.6 bar. Standard curve equation y = 1.074 x + 7.1124, R2 = 0.9977. Precision experiments RSD = 1.4%, repeatability experiment RSD = 1.8%, the stability experiment RSD = 1.8%. Recoveries=1.6%。...