| With greatly scale of electrophysiological simulation and the graduallyincreasing of the data quantity,we increasingly need a electrophysiologicalsimulation system that can make a real-time visualization and can have a control inall computal process. How to design and implement this system to meet our needsbecomes the starting point of this paper.As existing electrophysiological simulation system analyze data in traditionalpost-processing methods in which the system can not make a real-time visualizationand can not pause or suspend until computational process ends. The steeringelectrophysiological simulation system can make a real-time visualization and cantrack and intervene computational process. Based on tracking and steeringvisualization technology,this paper discuss the architecture of steeringelectrophysiological simulation system in detail.The realization of this system andthe application of steering technology in this system are researched systematicallyand thoroughly. The research includes following parts:(1) The basic principle of computational steering technology wasresearched.And the process and principle of steering electrophysiologicalsimulation were explored and studied.Finally, the computational steeringmechenism was integrated into process of electrophysiological simulation.(2) The composition of myocardial cell and the feature of every organizationwere researched, and then the simulating process of myocardial cell model wasresearched. Kinds of numerical algorithms were applied based on the previous study.Finally, kinds of numerical algorithms and kinds of myocardial cell models wereintegrated into electrophysiological simulation system.(3) The software framework of this patch-clamp simulation platform wasdesigned based on the design idea of Design Patterns and Object-Oriented, which isscalable, reusable, and maintainable. A steering electrophysiological simulationsystem was developed, which is workable, efficient, highly robust, and fullyfunctional. |
PDF Full Text Request