Sticking Efficacy Of Traditional Chinese Medicine Treatment Of Cancer Pain

Background:Cancer pen are chronic Pain, Including pain caused by cancer directly and the pain caused by antineoplastis therapy. Cancer pain is a common symptom in cancer patients.It is also one of the main causes of cancer patients fear, and sometimes even more than the threat of death. Painless is the basic state of people born with basic rights, basic needs.The World Health Organization Propose that "cancer pain can be controlled, it must be controlled."in1982.And developed a three-step treatment for cancer pain. Research shows that three-step program allows90%of cancer patients are effectively relieve pain. WHO recommends use of opioid analgesics in patients with cancer pain as a common painkiller. Although opioid analgesic efficacy more accurately, However, due to addiction, drug resistance and severe toxicity to benefit the population is limited. In order to alleviate the pain of cancer patients and improve their quality of life, In recent years, traditional chinese medicine use herbal oral, topical, acupuncture and other methods treat of cancer pain, and achieved more satisfactory results. traditional chinese medicine outside use with convenience, safety, and other advantages of small toxicity. This topic observation, analysis and summary of the efficacy of the way for pain relief. Aimed at reducing pain in cancer patients, reduce the use of opioid analgesics dose and toxicity, let cancer patients reached or almost reached painless purpose.Research Methods:Use a randomized controlled research Methods to do the Clinical research, The observed must met the inclusion criteria for the patients with cancer pain. Select the45patients admitted to hospital, Were randomly divided into experimental group (27cases) and control group (18cases).Control group was given painkillers accordance with the three-step analgesic ladder program, experimental group combine with traditional chinese medicine(times/day for5days). Comprehensive evaluation of opioids safety, analgesic effect, adverse reactions and patient satisfaction, quality of life. Through the chi-square test, the difference was statistically significant.Results:1. Aspects of pain relief:According to WHO Pain Evaluation Criteria and combined with NRS.45cases of cancer pain patients were randomly divided into treatment group and control group, Statistics found that the treatment group had6cases of CR, PR16cases, MR has4cases, NR1case; control group had3cases of CR, PR10cases, MR has4cases, NR1case. The chi-square test, the difference was statistically significant. Treatment group total efficiency of Pain relief was81.47%and control group total efficiency of Pain relief was72.23%. 2. Security aspects:45cases of cancer pain patients were conducted safety evaluation in5days before and after treatment, Including check liver and kidney function, ECG and other indicators. The security is divided into four (a security,2relatively safe,3moderate adverse reactions,4termination of the experiment). Were randomly divided into treatment group and control group. Statistics found that the treatment group had3cases of1,22cases of2,2cases of3,0cases of4; control group had3cases of1, llcases of2,4cases of3,0cases of4. The chi-square test, the difference was statistically significant. Treatment group total efficiency of security was92.59%and control group total efficiency of security was77.78%.3. Adverse reactions:The adverse reactions are divided into four degrees, Statistics found that treatment group1degree23cases,2degrees one case, security was88.9%;1degree13cases in the control group,2degrees one case, security was77.8%.4. Satisfaction with aspects of pain:The satisfaction is divided into four degrees, Including very satisfied, satisfied, in general, satisfied. The total treatment satisfaction (very satisfied and satisfied) was81.48%,66.67%in the control group.5.Improve the quality of life aspects:using Karnofsky grading a counting for-6.67±3.43of the total number of patients before treatment KPS score.By comparing the two groups after treatment NRS score found that Treatment group decreased NRS score was3.41±1.98points;NRS score was decreased in the control group2.33±2.37points.Improving the quality of life prove that the treatment group than the control group.6. The total amount of opioid analgesic drug use areas:calculate the total amount of the start of treatment on day1, day5patients with oral morphine. By comparing the the total amount of morphine, compare the analgesic effect of the two groups. Drug treatment group to reduce the average10.1lmg, the control group, the average-10.01mg. Two sets of data by t test, the difference was statistically significant (P<0.05). By calculating the total amount of morphine to the patient orally, treatment group Joint use of traditional Chinese medicine reducing the amount of morphine and reduce adverse reactions and improve the quality of life of patients, Relative to the control group, the patients were more likely to.7. Comparison of analgesic onset time and duration:treatment group onset of analgesia was18.7±7.6min;The duration of analgesic therapy group was21.11±6.0min.The duration of analgesic therapy group was6.31±5.35h;Duration of analgesia group was4.52±3.56h.Two sets of data by t test, the difference was statistically significant.Conclusions show that:chinese herb joint three-step analgesic onset time is shorter, and longer duration of analgesia.Conclusions:Chinese medicine for alleviating pain in patients with cancer has made satisfactory results. Through Observation of patient KPS, NRS score, Pain Degree,Safety and adverse reactions total use of analgesic drugs,patient satisfaction are discovered raditional Chinese medicine reducing the amount of morphine and reduce adverse reactions and improve the quality of life of patients, such as nausea, vomiting, diarrhea, constipation, fever, insomnia, anxiety and so on. In the treatment group, the incidence of adverse reactions, safety and other aspects are better than the control group. Effectively improve the quality of life of patients. Reflects the traditional Chinese medicine is simple, safe and effective features.