San Ren Tang Treating 30 Cases Of Phlegm Obstructive Sleep Apnea Syndrome Analysis

ObjectiveBy collecting patients diagnosed obstructive sleep apnea syndrome of phlegm in line with TCM, treat objects with Chinese medicine decoction—San Ren Tang, observe San Ren Tang efficacy to phlegm type OSAS patients, provide the basis for the system of traditional Chinese medicine syndrome differentiationMethodsThis study collect patients diagnosed OSAS with PSG monitored by monitoring room in Beijing Hospital, with sleep snoring at night obviously, daytime sleepiness, select30newly diagnosed adult patients diagnosed with OSAS of TCM phlegm block type filters which are willing to accept traditional chinese medical treatment and agree to regular follow. Use San Ren Tang (almonds10g, white cardamom6g, Coix seed30g, Magnolia10g, Processed Pinellia10g, Tongcao5g, short bamboo5g, talcum15g) treat objects, follow-up once a week, a month referral, the datas of clinical symptoms quant itative score, AHI index, Body mass index, neck circumference, waist circumference, hip circumference,ESS score, night-time lowest oxygen saturation (LSaO2), mean nighttime oxygen saturation (MSaO2), low-density lipoprotein cholesterol (LDL-C), after going to bed and waking blood pressure (Blood Pressure, BP) were compared. Using SPSS19.0statistical software for data analysis.Results30patients,20males and10females, aged55.13±12.51years of age, a history of snoring13.11±11.25. Use AHI as a standard, mild in9cases,10cases of moderate and severe in11cases. according to AHI, comparing before and after treatment showed significantly effective in7cases, effective in12cases,11cases, the total efficiency of63.33%(P=0.00). Among that, Mild patients, significantly effect in6patients (4males and2females), effective in3cases (one case of males,2females), no ineffective cases, the total efficiency is100%; moderate patients were cured,1patients (1males, females0cases),7cases (5males and2females),2ineffective cases (2males females0cases), the total efficiency is80%; severe in patients with markedly0cases,2effective cases (1male, female1case), ineffective (6males3females), the total efficiency is18.18%. Use quantify the total score of clinical symptoms as standard, effective in0cases, improved in27cases (18male, female9cases),3cases (2male, female1case), the total efficiency rate is90%(P=0.00). Symptoms in snoring, sleepiness drowsiness, dry mouth, fatigue, head and body weight difficulties, stool sticky, greasy, slippery pulse or moisten improved significantly after treatment, the difference was statistically significant (P<0.01), big fat tongue before and after treatment did not change significantly (P=0.317). LDL-C, LSaO2, MSaO2, ESS scores were significantly improved (P<0.05). OSAS patients generally awake after bedtime blood pressure compared with elevated blood pressure, elevated blood pressure using the morning after the San Ren Tang treatment conditions improved significantly (P<0.05). Before and after treatment BMI, NC, WC, HC do not significant change (P>0.1).ConclusionSan Ren Tang for phlegm OSAS efficacy, worthy of promotion. San Ren Tang is much more effective to mild or moderate OSAS, therefore, early Chinese medicine treatment can relieve symptoms and improve the condition. The datas shows BMI, neck circumference, waist circumference do not significant improvement before and after treatment, the mechanism of modern medicine for San Ren Tang treating OSAS needs further study. Because of the limited time, the sample size is small, the long-term follow-up study has not been conducted, the impact on disease control, the occurrence of complications, mortality rate is lack of information, pending further study.