Shufeng Xuanfei Particle Treatment Of Influenza (wind-heat Invading Lung Syndrome) Clinical Efficacy

Background:Influenza has brought serious harm to the society and spread widely in the world in epidemiological history.All of this because of its rapid got, spread fast and worldwide influenced.In Traditional Chinese Medicine influenza is also called epidemic cold. Compared with western medicine, Traditional Chinese Medicine has a great advantage in the prevention of influenza. These advantages mainly include of better curative effect, little side-effect, less resistance, strong pertinence and ect. Enxiang Chao is a professor of China-Japan Friendship Hospital, ShuFeng XuanFei KeLi is according to the many years of clinical experience of professor Chao. During the winter of2012, clinical study showed that ShuFeng XuanFeiKeLi has good effect in the treatment of influenza early.Objective:Through the clinical study to clarify the effectiveness of ShuFeng Xuan FeiKeLi in the treatment of influenza, relieve the flu symptoms, clarify Shufeng XuanfeiKeLi in shortening the course of influenza, and evaluate the safety of ShuFengXuanFeiKeLi.Method:This clinical study is a randomised, double-blind, placebo-controlled study. There are100copies of medicine50copies are Shu FengXuanFeiKeLi that is the antiflu medicine and placebo are50copies,and all of these100copies are random numbered. Choose patients with light syndrome of flu and type of wind-heat affecting lung in TCM, give patients one copy one time, twice a day,and last3days. After3days review the patients by taking telephone, and records detailed.Results:The subjects include75patients,38male patients and32female patients, the average age is (30.46±1.05).There are5cases fall off, loss rate is6.7%. Patients were randomly divided into two groups, one is treatment group which take ShufengXuanfeiKeLi and the other is control group which take placebo.There are37patients in the treatment group and33patients in the control group. In the control group, there are16male patients and17female patients.In the treatment group,there are22male patients and15female patients. The average age of the control group is (30.19±1.59) and the average age of the treatment group is (30.70±1.41). The average course of disease in the control group is (27.06±1.70) h, and (34.46±1.75)h in the treatment group. There is no adverse reaction after taking medicine. After the treatment, the average of symptom scores in control group is (4.03±0.60), and (3.51±0.52) in the treatment group, p=0.585.But according to the clinical significance,the treatment group in relieving clinical symptoms is better than the control group. The control group take (34.84±3.86)h to bring down the fever and the treatment group take (31.16±3.23) h, P=0.573, no significant difference.Before treatment the symptom score oftreatment group is(19.86±0.86), andafter treatment thesymptom score is(3.51±0.52), p<0.05, the difference is statistically significant.Conclusion:ShuFengXuanFeiKeLi has obvious curative effect of influenza early syndrome in the treatment. ShuFengXuanFeiKeLi could relieve the mainly clinical symptoms of influenza, and shorten the course of the disease. This study showed that ShuFengXuanFeiKeLi had no adverse reaction. Results of the clinical research are not have statistically significant difference. This mainly due to the less number of cases, so we need to continue to collect many more cases for the study.